Yuvafem is a branded-generic vaginal insert that’s prescribed for certain symptoms of menopause. It’s available as the brand-name drug Vagifem. The cost of Yuvafem, with and without insurance, can depend on several factors.

Yuvafem is prescribed to treat vaginal inflammation, dryness, and thinning that can occur with menopause.

As with all medications, the cost of Yuvafem can vary. Factors that may affect the price you’ll pay include your treatment plan, your insurance coverage, and the pharmacy you use.

To find out what the cost of Yuvafem will be for you, talk with your doctor, pharmacist, or insurance provider. Or look below in the next section to learn how much you can save by using an Optum Perks coupon.

To save money on your Yuvafem prescription, explore these Optum Perks coupons.

Save on Yuvafem with Optum Perks

Save on yuvafem without insurance.

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10mcg yuvafem (8 Tablets)

Save money without using insurance

Simply show the Optum Perks coupon at your preferred pharmacy or order online and instantly save up to 80% without using insurance. The coupon doesn’t expire, so be sure to save it for refills.

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Retail price refers to the manufacturer’s published list price and is up to date as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.

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Pricing source:Perks.optum.com


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Yuvafem is a branded-generic drug, which means it’s an exact copy of the active ingredient in a brand-name medication. It contains the active drug, estradiol. Usually, generic drugs are referred to by the name of their active drug(s). But branded-generic drugs are given a trade name by the manufacturer. They’re considered to be as safe and effective as the original drug. And branded generics tend to cost less than brand-name drugs.

Yuvafem is available as the brand-name drug Vagifem. If your doctor has prescribed Yuvafem and you’re interested in receiving Vagifem instead, talk with your doctor. They may have a preference for one version or the other. You’ll also need to check with your insurance provider, as it may only cover one or the other.

To find out how the cost of this brand-name drug compares with the cost of Yuvafem, talk with your doctor, pharmacist, or insurance provider.

If you receive Yuvafem long term, you may be able to lower its cost in the following ways.

Getting a 3-month supply

You may be able to get a 90-day supply of Yuvafem. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. If you’re interested in this option, check with your doctor, pharmacist, or insurance provider.

Using a mail-order pharmacy

Yuvafem may be available through a mail-order pharmacy. Using this type of service may help lower the drug’s cost and allow you to receive your medication without leaving home. Some Medicare plans may help cover the cost of mail-order medications. You may also be able to get a 90-day supply of the drug via mail order.

If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need financial support to pay for Yuvafem, consider looking into websites that offer cost resources and information. Two such websites are:

These sites can provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services.

Here are answers to some frequently asked questions about drug cost and Yuvafem.

What’s the cost of Yuvafem without insurance?

The price you’ll pay for Yuvafem if you don’t have insurance can vary based on several factors. But typically, the cost is higher for those without insurance.

There are other factors that could affect what you pay for this drug. These include:

  • the quantity you’re prescribed (such as a 90-day or 30-day supply)
  • whether you apply and qualify for any available savings programs
  • your dosage
  • the pharmacy you use

To learn the exact cost you’d pay for this medication without insurance, ask your doctor or pharmacist. You may also want to contact several pharmacies to compare their prices for Yuvafem.

Check out Optum Perks* for estimates of Yuvafem’s price when using coupons from the site. (Optum Perks coupons cannot be used with insurance benefits or copays.)

* Optum Perks is a sister site of Medical News Today.

Is Yuvafem covered by Medicare?

It may be. You can call your Medicare plan provider to learn whether your particular plan covers the cost of this drug. There are many types of Medicare plans, so your coverage and what you pay for prescriptions will be based on your particular plan’s benefits.

You may also need to obtain prior authorization before your plan will cover the cost of this medication.

Your doctor may have information about your cost for Yuvafem if you have Medicare.

Below is information you may want to consider if you have insurance and receive Yuvafem.

If you have insurance, your insurance company may require prior authorization before it covers Yuvafem. This means the company and your doctor will discuss Yuvafem in regard to your treatment. The insurance company will then determine whether the medication is covered. If a drug requires prior authorization but you start treatment without the prior approval, you could pay the full cost of the medication. You can ask your insurance company whether Yuvafem requires prior authorization.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.