The Moderna vaccine is one of the vaccines that offer protection against SARS-CoV-2, the virus that causes COVID-19. Booster doses provide additional protection.

The Moderna vaccine is a vaccine that protects against the virus that causes COVID-19.

This article explores the Moderna vaccine in more detail and discusses its effectiveness and protection against variants, among other factors.

Learn more about the Moderna vaccine here.

a clinician administering Moderna vaccine to a patientShare on Pinterest
Hannah Beier/Bloomberg via Getty Images

The Moderna vaccine is available in two doses for people aged 6 months and older. People should receive the second dose at least 4 weeks after receiving the first one.

However, according to the World Health Organization (WHO), it may be best to have an 8-week interval between the two doses. This longer interval between doses may help increase the vaccine’s effectiveness and reduce the risk of myocarditis.

A booster dose may be beneficial for those who have received both doses. According to the WHO, the Moderna vaccine provides high effectiveness when people receive the two doses and the booster dose.

The Moderna vaccine is more than 90% effective when people receive the second dose. Researchers found that Moderna was 92% effective 120 days after the second dose. The Pfizer vaccine’s effectiveness went down to 77% after the same amount of time.

Scientists do not know which vaccine will last longer than others. However, researchers in a 2021 study found that the Moderna vaccine was more effective than the Pfizer vaccine.

Also, the Centers for Disease Control and Prevention (CDC) suggest that the Moderna vaccine may offer better long lasting protection than other vaccines. One 2021 study indicates that immunity may last 6 months when a person receives both Moderna doses.

In 2022, the Food and Drug Administration (FDA) approved a bivalent Moderna booster, which targets two different antigens in one dose. This means it should be effective against the original strain of the SARS-CoV-2 virus and some Omicron variants.

Other vaccines, such as those from Pfizer-BioNTech and Johnson & Johnson, also provide COVID-19 protection.


The Pfizer-BioNTech vaccine is available in 2 doses that people receive 21 days apart. Its effectiveness in preventing people from contracting SARS-CoV-2 is about 95%.

It offers immunity 2 weeks after a person receives the second dose. According to the manufacturer, this effect may last at least 6 months.

One study found that the Pfizer vaccine is more effective against the Alpha variant than the Delta variant.

Like the Moderna vaccine, a bivalent Pfizer-BioNTech booster has FDA approval.

Learn more about the Pfizer vaccine here.

Johnson & Johnson

The Johnson & Johnson vaccine is available for adults aged 18 and older. It comes as one dose, which provides immunity after 2 weeks.

This vaccine is about 66.3% effective against COVID-19. It also helps reduce the chance of hospitalization.

Learn more about the Johnson & Johnson vaccine here.

Vaccines do not offer protection immediately. A person will typically gain immunity 2 weeks after getting a second or third dose.

The Moderna vaccine is also more effective after the second dose and booster dose.

According to the WHO, the Moderna vaccine effectively protects against virus variants. However, it seems more effective in preventing severe disease from Delta when a person takes the two doses.

The Moderna and Pfizer vaccines should be effective against COVID-19 variants. Companies aim to create vaccines that recognize different parts of a virus to protect against new variants.

Recent research found that the booster is more effective against Delta than Omicron symptoms. However, it helps reduce COVID-19-related hospitalization and mortality rates, regardless of the variant.

The WHO states that the Moderna vaccine is safe for people of all ages, especially older adults, healthcare professionals, and people with compromised immune systems. People over 65 who receive Moderna’s 2 doses have a 94% reduced risk of needing hospitalization if they develop COVID-19.

People who have contracted SARS-CoV-2 can also receive vaccines, but they may have to wait until 3 months after they recover.

A single booster dose may also benefit those 18 years and older who have completed their full vaccination therapy in the previous 5 months.

The Moderna vaccine is safe for people aged 6 months and older.

People get two doses, usually 8 weeks apart, to increase the vaccine’s effectiveness and reduce their chance of developing side effects. Vaccinated people are also less likely to develop severe symptoms or need hospitalization for COVID-19 symptoms.

It takes 2 weeks after receiving a final dose for a person to develop immunity.

The Moderna vaccine is also effective against variants, but studies have shown that it provides more protection against Delta than Omicron.