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Lipozene is a popular diet pill for weight loss. It contains a soluble fiber called glucomannan that absorbs water to create a thick gel. This fiber may have links to weight loss.

Lipozene may have potential benefits for some people. However, the weight loss effects are usually mild, and this diet pill may be unsuitable for some.

Diet pills, such as Lipozene, are not replacements for proven weight control methods, such as eating a nutritious diet and exercising regularly.

This article explores the safety of Lipozene as well as its benefits, side effects, and effectiveness.

Lipozene is a branded dietary weight loss supplement that contains glucomannan as an active ingredient. Glucomannan is a fiber from the root of the konjac plant, Amorphophallus konjac.

Glucomannan is a soluble fiber that absorbs many times its weight in water. Because of this, konjac products are popular thickeners in some foods.

The konjac root and its compounds are popular weight loss aids because of this fiber and its ability to absorb water.

Learn more about the benefits of konjac.

Before trying Lipozene, people should consider the advantages and disadvantages of the supplement.


  • may enable weight loss
  • may prevent a person from overeating
  • may reduce the absorption of fat
  • may work as a prebiotic, increasing healthy bacteria in the intestines
  • is additive-free
  • is laxative-free
  • is stimulant-free
  • may reduce levels of glucose
  • may reduce cholesterol
  • may reduce fats in the blood
  • may lower blood pressure


  • only yields mild, inconsistent weight loss in research studies
  • is unsuitable for vegetarians or vegans
  • may reduce the effectiveness of certain medications
  • may cause stomach discomfort, nausea, diarrhea, and constipation
  • there is a risk of choking
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Glucomannan primarily encourages weight loss through its ability to rapidly absorb water from the upper gastrointestinal tract, increase in size, and form a gel in the stomach. This makes people feel full, and they may eat less as a result.

However, the authors highlight that scientific data proving its beneficial effect on weight loss is inconsistent and that more research is necessary.

Other research shows that viscous soluble fiber, which includes glucomannan, is more likely to encourage satiety than nonviscous types. This is because it delays the processes that empty the stomach, which keeps food in the stomach for longer and slows down digestion and nutrient absorption.

Viscous soluble fiber can also increase the level of short-chain fatty acids (SCFAs) in the body, which can regulate the production of peptides that regulate the appetite. This can also increase a person’s satiety and reduce the amount of food they eat.

The National Institutes of Health (NIH) state that there is limited high quality research on the long-term effects of glucomannan for weight loss. It warns that taking glucomannan supplements for short-term use may cause minor side effects, such as diarrhea, constipation, and bloating. It also discusses important safety concerns, such as the risk of choking if the supplement forms a gel in the throat.

Typically, the effectiveness of Lipozene for weight loss is mild. A 2020 study suggests that glucomannan supplements may be effective for people who have obesity. However, there are conflicting reports about its effectiveness.

However, these effects may not apply to everyone. According to a 2019 study, glucomannan did not appear to be more effective than placebo treatment in reducing the body mass index (BMI) of children with overweight and obesity.

The study included 96 participants aged 6–17 years who received glucomannan and maltodextrin supplements for 12 weeks. While glucomannan did not affect BMI scores, it did lower total and low-density lipoprotein cholesterol (LDL), also known as “bad” cholesterol.

Additionally, an older 2013 study on adults with obesity suggests glucomannan does not promote weight loss, alter body composition, or change feelings of hunger or fullness.

For some people, these mixed results may be enough to justify taking Lipozene to boost their diet and weight loss goals. Others may feel these do not justify the cost or potential side effects.

Learn more about the effectiveness of weight loss pills.

Lipozene may be suitable for those who wish to lose weight by reducing their calorie intake.

It may also suit people who want to try a low calorie weight loss pill that uses natural active ingredients. However, Lipozene contains gelatin, meaning it is unsuitable for vegetarians or vegans.

In a 2020 study, researchers found that another glucomannan weight loss brand, PGX, had weight loss benefits in people with overweight and obesity. However, results are inconclusive, and there is little data on how long the weight loss effects may last.

Other people who Lipozene may not be suitable for include those with diabetes. This is because it can block the absorption of some diabetes medications. It can also lower blood glucose, making it potentially unsuitable for people who take medication to lower blood glucose.

Additionally, those who have difficulty swallowing tablets or capsules may wish to avoid Lipozene.

A person needs to always consult a doctor before trying Lipozene to ensure it is safe for them to take.

The active ingredient in Lipozene, glucomannan, is typically safe to consume in amounts of up to 3 grams (g) a day. This is less than the company suggests, which recommends people take up to 4.5 g a day.

Research states that doses higher than 3 g may cause digestive discomfort.

However, it is important for a person to stay well hydrated when taking glucomannan products because it can absorb up to 200 times its weight in water.

Additionally, glucomannan capsules may be safer than powders. As a very absorbent substance, glucomannan can expand before it reaches the stomach, increasing a person’s risk of choking or creating a blockage in their digestive system.

Individuals should not exceed the company’s recommended dose and follow instructions on how and when to take Lipozene.

The benefits of glucomannan relate to its specific type of soluble, fermentable dietary fiber.

A 2019 review notes that glucomannan fiber may help:

Many of these benefits come from how glucomannan behaves in the body.

The sections below detail some specific potential benefits.

It may keep the body full

Taking Lipozene with a full glass of water before each meal creates a thick, gel-like substance in the stomach. This substance leaves less room in the stomach for food.

Because of this, a person who takes Lipozene may feel full sooner, which may reduce the chance of overeating.

It may reduce calories from meals

As glucomannan can make a person feel full, it might reduce the number of calories a person eats with each meal. If someone consumes fewer calories than they burn each day, this could lead to weight loss over time.

The fiber itself is also low in calories, so taking it does not add much to the diet.

It may reduce caloric intake from other sources

Glucomannan may also help a person lose weight by reducing the energy they absorb. Soluble fibers, such as glucomannan, may reduce the absorption of nutrients, such as fats.

This means that the body might take up less energy from these food sources and instead pass these calories out with waste.

It is a source of prebiotic fiber

Glucomannan fiber is also prebiotic. This means that it feeds the healthy bacteria that colonize the intestines.

The 2019 review notes that the stomach does not digest the fiber. Instead, it passes through to the intestines, where the intestinal bacteria can ferment it and use it as fuel.

This process is important, as the health of the intestinal microorganisms influences the overall well-being of the body.

A 2018 study notes the benefits of prebiotic compounds, including their ability to:

  • increase healthy bacteria in the intestines
  • increase mineral absorption
  • decrease harmful bacteria in the gut
  • decrease allergy risk
  • cut the harmful fermentation of proteins in the gut
  • improve the immune system response

Although not every prebiotic fiber will act the same way, eating a diet rich in prebiotics may help ensure that the intestinal flora is healthy.

It has simple active ingredients

Another potential benefit is that Lipozene is a relatively simple form of weight loss supplement.

Although some pills may contain stimulants, laxatives, or other additives, the only active ingredient in Lipozene is glucomannan.

So, the product may be an option for people looking for more straightforward ingredients to help them with weight loss.

Lipozene has a D+ rating on Better Business Bureau (BBB) but does not hold the platform’s accreditation. It has no reviews and has closed 20 complaints in the past 3 years.

Lipozene.com is registered with Trustpilot, where it has an average rating of 2.5 out of 5 stars based on five reviews.

Reviewers claim that the product does not work and the website does not provide accurate information. Buyers also did not like that they could only buy the supplement on subscription, and some had problems canceling the auto-renewal.

However, one customer wrote that it helped to reduce their cravings, although it did not help them lose weight.

Lipozene failed Medical News Today‘s thorough vetting process. This is because of limited scientific evidence proving the efficacy of its active ingredient, glucomannan, and safety concerns, including obstructions of the bowel and esophagus.

Additionally, the company does not consistently use the required Food and Drug Administration (FDA) disclaimer when making claims about the health benefits of its products. It also does not provide full dosage information for all of the ingredients in its products.

Most people tolerate glucomannan well. However, some people may be more sensitive to soluble fibers, and mild reactions in the digestive system may occur.

Mild side effects from taking glucomannan may include:

Some side effects may be worse if the person does not drink enough water with glucomannan, as the fiber may take water from the body.

Glucomannan may also reduce the absorption of certain medications. A person can talk with a doctor before taking Lipozene to ensure that it will not interact with any of their medications.

Lipozene states that pregnant and lactating people should not use its products.

The following sections look at some specific risks in more detail.


There is a risk of choking if an individual does not drink enough water along with Lipozene capsules. Specifically, if the capsules become stuck in the throat, they may expand and swell, blocking the esophagus.

For this reason, people who have difficulty swallowing capsules should avoid Lipozene.

Anyone who is experiencing serious side effects after taking Lipozene — such as chest pain, difficulty breathing, or difficulty swallowing — must seek immediate medical attention.

Reactions from other ingredients

Although glucomannan and konjac root are not common allergens, some people may be more sensitive to the added ingredients in Lipozene.

Aside from glucomannan from the konjac root, Lipozene capsules also contain:

  • gelatin
  • microcrystalline cellulose
  • magnesium silicate
  • stearic acid
  • titanium dioxide
  • FD&C Blue #1

Lipozene recommends people take a two-capsule serving of Lipozene 30 minutes before a meal with 8 ounces of water. People can take Lipozene three times a day, with a maximum of six capsules throughout the day. This is equivalent to three 1.5-gram doses spread throughout the day.

At the time of publishing, Lipozene costs $29.95. Each bottle contains 60 capsules, equal to 30 two-capsule servings.

Lipozene also offers promotions, such as buy one get one free. There is also a processing fee of $1.35 during shipping, and a $1.35 fee if a person returns the supplement. People have 30 days to return the product for a refund after they receive it.

Taking glucomannan or Lizopene for weight loss appears to produce mild results in some cases. However, no dietary supplement is a replacement for other healthy weight loss habits.

Anyone who is looking to lose weight will still need to make changes to their diet and lifestyle. These changes often include eating a healthy diet, reducing caloric intake, and getting regular exercise.

Anyone who is worried about their weight should work with a doctor to create an individualized plan for weight loss.

Learn how to lose weight fast naturally.

There is a variety of weight loss methods and tools people can try besides weight loss supplements. We look into these alternatives in more detail below.

Eating a nutritious diet

Eating a balanced diet is important for maintaining optimal health. A diet that reduces carbohydrate and fat intake may help weight loss. However, people can work with a registered dietician or another doctor to curate the best diet for their body, dietary needs, lifestyle, and weight loss goals.

The Dietary Guidelines for Americans 2020–2025 recommends people eat the following for a healthy, balanced diet:

  • all types of vegetables, including leafy greens and starchy vegetables
  • whole fruits
  • grains, half of which should be whole grain
  • dairy, including fat-free, low fat, lactose-free, and soy milk, yogurt, and cheese
  • protein, such as lean meat, poultry, legumes, and soy products
  • oils, such as vegetable oils

People should limit the amount of food they eat with high sodium, added sugars, and saturated fats.

The Department of Agriculture offers a free tool called MyPlate that people can use to plan their diet according to their age, sex, height, weight, and activity levels.

Meal planning

The Academy of Nutrition and Dietetics suggests that meal planning may be helpful for people who have a busy schedule. A person may decide to prepare meals for a whole week on a specific day and then store them in a freezer. If they have enough storage space, they may prepare their dishes a month ahead.

The organization also recommends cooking meals depending on the weather, such as soups in winter and salads in summer.

According to the American Diabetes Association, it may be best to avoid buying products that contain added sugar or processed foods.

However, people need to speak with a doctor before changing their diet to lose weight.

Meal kit deliveries

Although people can meal plan and cook food in batches to eat throughout the week, others may prefer to use meal kit delivery services. Some brands offer weight loss menus that include low calorie meals.

Some meal kit delivery services include:

  • Blue Apron: This company offers low calorie, carbohydrate-conscious, and diabetes-friendly meals. Blue Apron also sells meals that contain 600 calories or fewer. Learn more about Blue Apron.
  • Trifecta: This company offers meals that contain 350–500 calories, which may help support weight loss. Trifecta uses organic ingredients and has meals suitable for people with ketogenic, paleo, and plant-based diets. Learn more about Trifecta.
  • Factor: This company states that most of its meals contain around 600 calories. Factor has meals that are suitable for people with various diets, such as low calorie, high protein, and plant-based. Learn more about Factor.

People should ensure they are getting a balanced diet and enough calories per day through their meal delivery kits.

Learn more about meal kits for weight loss.

Physical activity

People can also engage in regular physical activity to lose or maintain weight.

The Centers for Disease Control and Prevention (CDC) state that people should not rely on physical activity alone to lose weight. A combination of eating a balanced and nutritious diet and regular exercising is more likely to help a person reach their health goals.

People need to aim for 150 minutes of moderate-intensity cardio, 75 minutes of vigorous-intensity cardio, or a combination of the two per week. Getting this amount of activity can help people maintain weight loss and lose weight while eating a nutritious diet.

Weight loss tools

People may use online tools to help them reach their target weight goal. These include WW (formerly Weight Watchers) and Noom.

WW is a doctor-recommended weight loss program that offers personalized plans for its users. It focuses on the calories that a meal as well as the amount of fiber, added sugars, and protein it contains. People using WW will track their food each day.

It offers 24–7 support, and people can also access a food, water, and sleep tracker. Learn more about WW.

Noom offers psychology-backed lessons and personalized courses to help people understand their relationship with food and eating habits.

Users work with a personal coach who guides them through their weight loss journey. The Noom smartphone app also comes with a food tracker and step counter to help individuals track their progress. Noom works similarly to WW in that it ranks foods. Learn more about Noom.

Learn how WW and Noom compare.

Anyone considering Lipozene needs to speak with a doctor or qualified nutrition professional before making a purchase. A person can consult a doctor about their weight loss goals and medical history to make sure that Lipozene will be safe for them to use.

The manufacturer states it is not aware of any medications or supplements that Lipozene can interact with. However, a person needs to consider any medication they take and discuss this with a doctor before trying it.

Additionally, some people may experience side effects while taking Lipozine, including stomach discomfort, nausea, diarrhea, and constipation. Those who experience these side effects should stop taking this diet pill and consult a doctor.

Additionally, anyone experiencing chest pain, difficulty breathing, or difficulty swallowing after taking Lipozene needs to seek immediate medical attention.

To get advice on how to lose weight safely, a person can speak with a licensed dietitian or doctor.

Eating disorders

People can have complicated relationships with food, weight, and dieting. Anyone with concerns about their weight or the effect dieting or weight loss supplements are having on their mental health can speak with a doctor.

In some cases, those trying to lose weight may be living with or developing an eating disorder.

Eating disorders include:

  • Anorexia nervosa: This very dangerous condition sees people avoiding food or severely restricting their food intake. They may weigh themselves very regularly and have an intense fear of gaining weight.
  • Bulimia nervosa: People with this eating disorder often eat large amounts of food followed by fasting, forced vomiting, overuse of laxatives or diuretics, or excessive exercise. These individuals may have a low, moderate, or high body weight.
  • Binge eating disorder: People with this disorder have difficulty controlling their food intake and regularly eat very large amounts of food. They do not “purge” their food intake with forced vomiting or laxatives with this condition. As such, those with a binge eating disorder often have overweight or obesity.
  • Avoidant restrictive food intake disorder: This condition has links to children, but it occurs in adults too. People with the condition will limit the amount of food or the types of food they eat. This can result in a low calorie intake that can affect body functions and health.

Treatments for these eating disorders may include medications and therapy.

Below are answers to the top frequently asked questions about Lipozene.

What do people use Lipozene for?

Lipozene is a dietary weight-loss supplement. It may help reduce a person’s appetite and make them feel full more quickly when they eat.

Does Lipozene lower cholesterol?

Research suggests that glucomannan, the active ingredient in Lipozene, may help reduce cholesterol.

Is Lipozene dangerous?

Research shows that most people have a good tolerance for the active ingredient in Lipozene, glucomannan. However, it may cause mild side effects, such as stomach pain, gas, constipation, and diarrhea.

There is also a risk of choking on Lipozene capsules. This is because glucomannan is extremely effective at absorbing water. Therefore, if a person does not swallow capsules with plenty of water, it can expand in the throat and become a choking hazard.

Glucomannan may also reduce the absorption of some medications.

A person always needs to speak with a doctor before trying Lipozene for weight loss.

How many Lipozene pills does a person need to take daily?

Lipozene states people can take three servings of 2 capsules daily. People should not take more than 6 capsules throughout the day.

What is the most successful weight loss pill?

People should always work with a doctor before trying a weight loss pill.

Prescription weight loss medications in combination with exercise and a balanced diet are more likely to be effective than over-the-counter medication. This includes FDA-approved medications, such as GLP-1 agonists, liraglutide (Saxenda), and others, such as orlistat (Xenical) and setmelanotide (Imcivree).

Lipozene is a dietary weight loss supplement with limited scientific research backing its effectiveness and safety. The active ingredient, glucomannan, is a natural fiber that may benefit weight loss when a person takes it regularly with plenty of water.

No supplement can replace dietary and lifestyle changes for weight loss. Taking Lipozene may help support weight loss efforts for some people, though any additional weight loss resulting from the supplement is typically mild.