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There are many options for treating premature ejaculation (PE), including prescription and over-the-counter (OTC) medications. Examples of pills include sildenafil (Viagra) and tadalafil (Cialis).
- Best for free consultations: Roman | Skip to review
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PE is a type of sexual dysfunction that affects up to
While lifelong PE has no cure, symptoms may resolve in
Please note that the writer of this article has not tried these products. All information presented is purely research-based and correct at the time of publication.
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It is always best to speak with a doctor about medication for treating PE, as some pills for the condition may interact with other drugs or existing health conditions. The safest option is to consult a medical professional for recommendations.
Some prescription and nonprescription pill medications that may help with PE
- certain erectile dysfunction (ED) medications
- analgesics, which are medications that relieve pain
Using some of these medications for PE would constitute an “off-label” use. This means that a doctor has prescribed a particular medication for a condition or at a dosage other than what the Food and Drug Administration (FDA) has approved.
Certain ED medications can also help treat PE. Taking these to treat PE is an off-label use.
The overall benefits of PDE5 inhibitors are similar to those of other medications and include better ejaculation control, improved confidence, and delayed ejaculation.
All the above ED medications are available via prescription.
Additionally, those looking to use off-label ED drugs, such as Viagra, must be aware of how they may interact with other medications. For example, health experts warn that individuals should not combine the hypertension drug riociguat with ED medication.
Although the everyday use of antidepressant medication is to treat individuals with depression and anxiety, several studies suggest the off-label use of two types of antidepressants may help treat PE by delaying ejaculations. These are SSRIs and tricyclic antidepressants (TCAs).
A person could take SSRI medications daily or as needed to manage PE, depending on their active ingredients. It takes
Availability can be an issue, as most antidepressant medications the
Antidepressants commonly cause side effects, such as:
It also lists some medications that individuals cannot take with antidepressants, including:
- monoamine oxidase inhibitors
Individuals looking to take tramadol should be aware that the FDA warns of the serious risks of combining this drug with benzodiazepines. This can be fatal.
Codeine is another type of analgesic drug. Using codeine for PE is an off-label use.
The individual in the study above developed a dependency on codeine, which is a derivative of opium. The authors state that while there were no liver or blood sugar abnormalities, this person had to undergo a 6-month withdrawal process.
It is best for people considering taking codeine to treat PE to consult a doctor to determine the best course of action and limit side effects.
Doctors can advise people on PE treatments that will not conflict with existing health conditions or medications. After people get this advice, they can buy PE medication from the following direct-to-consumer health companies that ship products across the United States.
Customers need to create profiles on the companies’ secure platforms and include their medical history and symptoms.
A healthcare professional will then review the person’s application before answering any questions they may have, describing potential treatments, and approving medication.
Numerous PE pills on the market reportedly do not work or contain untested amounts of prescription medication.
For example, the
It is best to avoid pills that companies market as PE treatments with unsubstantiated health claims or those that do not have any research to support their benefits. People should not use PE treatments that do not clearly list the ingredients on the packaging.
It is always best to consult a doctor to find the safest and most effective treatment for PE.
There are primary and secondary triggers for this condition:
The following may trigger PE:
- a person’s upbringing
- conditioning by family and society
- traumatic sexual experiences
Several health conditions that may trigger or worsen PE include:
Individuals with concerns about PE may wish to try OTC products and exercises before considering medication or surgical treatments. Alternative treatments for this condition include:
Pelvic floor exercises
Condoms and wipes
Certain condoms and wipes may help reduce stimulation and delay ejaculation. However, no studies have looked at the long-term treatment of PE when individuals have relied solely on condoms or wipes.
Sprays and creams
Some sprays and creams that contain desensitizing ingredients can decrease stimulation.
There are various investigational surgical treatments that individuals with moderate to severe PE can consider,
- Glans augmentation: A surgeon injects hyaluronic acid and a bulking agent into the glans of the penis to reduce nerve sensitivity. A
2021 studyreports a decrease in PE among participants who underwent glans augmentation.
- Varicocelectomy: This surgery removes swollen veins from inside the scrotum. A 2020 study suggests that participants found an overall improvement in both testosterone levels and PE after a varicocelectomy.
- Pulsed radiofrequency neuromodulation: According to a
2021 study, this procedure uses radiofrequency to treat the penile nerves. Recipients showed significant improvements in PE and had no side effects after the procedure.
A person may consider talk therapy to work on any anxiety related to sex or relationships. This may help them identify and address underlying emotional issues relating to PE.
A 2019 study looked into the reliability of YouTube videos for treating PE. The authors concluded that the video platform was helpful and most videos had reliable information.
However, it is important to exercise caution when getting advice from the internet, as not all content creators offer reliable or safe information.
Before acting on advice found online, it is always best to speak with a doctor.
Some home treatment methods for PE
- trying techniques for delaying an orgasm
- using thicker condoms to decrease sensation
- masturbating 1–2 hours before sex
- exercising regularly
- resting well
- eating plenty of fruits
People can also try extending foreplay and using alternate sex positions.
The “squeeze” technique
Once a person reaches their point of no return, they hold their thumb over the frenulum and two fingers on the opposite side of the glans. They then squeeze for a few seconds until the desire to ejaculate passes.
People may instead wish to contract their pelvic floor muscles, which may provide the same results.
The “stop-start” technique
Some people may use this method during penetrative sex. It requires a person or their partner to stimulate the penis until the person reaches their point of no return. Then, they should cease all stimulation until the desire to ejaculate passes.
The below table compares some of the treatments for PE.
|PDE5 inhibitors including:|
• Sildenafil (Viagra)
• Tadalafil (Cialis)
• Vardenafil (Levitra)
• Avanafil (Stendra)
|prescription only||around $2–$20 per dose for generic options, plus consultation fees where applicable|
|Antidepressants, including SSRIs and TCAs||prescription only||varies by drug|
|over the counter from drug stores and online companies||around $19–90|
|Surgical options||inpatient or day-case treatment only||varies by surgical option|
|Therapy||online or in person||varies by provider, but often around $60–150 per week for online options|
People can contact a doctor if they believe they are ejaculating too soon while engaging in sexual activity.
- how often and for how long the person has been experiencing PE
- whether this happens with one partner or has happened with several
- whether the person experiences PE with every sexual activity, including masturbation
- whether there is anything, such as drugs or alcohol, that makes PE more or less likely
After taking a history and diagnosing PE, a doctor may prescribe medication.
This varies depending on a person’s needs. Some people may find SSRIs most effective as they take them daily. Others may prefer to use PDE5 inhibitors, which they take as and when needed. A doctor will be able to recommend the most appropriate medication.
Yes, some pills can help premature ejaculation. Antidepressants and PDE5 inhibitors such as Viagra, can stop people from climaxing early.
There are several medical and psychological causes for premature ejaculation, such as:
- nontypical hormone levels
- sleep deprivation
People who do not last as long in bed as they want may wish to speak with a doctor to see if there are any underlying conditions. Healthcare professionals can help find and treat any conditions impacting performance in bed.
There are several pills that may help people last in bed, including:
- PDE5 inhibitors, such as sildenafil, tadalafil, and vardenafil
Numerous OTC and prescription pills may help treat PE. Many of these options involve off-label use for the condition, meaning their primary use is for treating other health issues, but they may treat PE incidentally.
Not all individuals with PE can take some of these pills because of their side effects and drug interactions. Before considering prescription medication or surgery, people may first want to try proven OTC and exercise treatments for PE.
It is best to consult a doctor to find the most effective and safest pill options for PE.