Small-cell lung cancer treatment often includes medication like chemotherapy or immunotherapy. Usually, doctors will treat this type of cancer with a combination of medication and other types of treatment.
Small-cell lung cancer makes up about
Small-cell lung cancer tends to cause a more aggressive form of cancer that spreads to other body areas more quickly. Since it spreads more quickly, surgery tends to be less effective for treating this type of cancer.
Cancer treatment teams often recommend medications or a combination of treatment options. This article explores the goal of small-cell lung cancer medications, the types of treatments, and their possible side effects. We also look at other treatments and the general outlook.
The goal of medications for treating small-cell lung cancer includes eliminating cancer cells and relieving symptoms. The type of medications recommended and the treatment goals depend on the cancer stage when diagnosed.
Usually, the treatment team prescribes medications to cure the body of the cancer cells. However, in more advanced stages of cancer where remission is unlikely, medications may help reduce symptoms and provide comfort.
According to a
A chemotherapy medication called Etoposide works by slowing down or stopping the growth of cancer cells. A healthcare professional may prescribe Etoposide as an oral or IV medication directly into the bloodstream.
Possible side effects
- nausea and vomiting
- stomatitis — inflammation of the mouth
- hair loss
- changes in blood pressure
- flushing
Cisplatin, a chemotherapy medication, targets and kills quickly dividing cells, such as cancer cells. People prescribed this medication usually receive it as an IV into their veins or artery.
Possible side effects
- nausea and vomiting
- diarrhea
- hair loss
- changes to taste
- hiccups
- dark urine
- dry mouth
- less sweating
- dry skin
- dehydration
Another type of chemotherapy medication, carboplatin, disrupts the growth of cancer cells and prevents them from splitting into more cells.
Possible side effects
The label lists possible side effects as
- nausea and vomiting
- diarrhea
- loss of appetite
- hair loss
- numbness
- tingling, burning, or pain in the hands or feet
Irinotecan, a type of chemotherapy, works by blocking an enzyme that cells use to grow and divide. Without this enzyme working properly, cancer cells stop dividing and spreading. When prescribed Irinotecan, people receive intravenous infusions to administer the medication.
Possible side effects
- neutropenia, a person has too few white blood cells and an increased risk for other infections
- diarrhea
- nausea and vomiting
- hair loss
- fatigue
Atezolizumab (Tecentriq), an immunotherapy medication, helps the immune system work properly to find and kill cancer cells. This medication is only approved by the FDA approved for administration through IV.
Possible side effects
- nausea
- back and neck pain
- low appetite
- rash
- cough or trouble breathing
- fatigue
- constipation
- diarrhea
- abdominal pain
- increased infections, such as urinary tract infections
- anemia
- altered liver or kidney function
Durvalumab (Imfinzi), an immunotherapy medication, helps the immune system target cancer cells by marking a mutated protein making it easier for the body to kill those cells.
Possible side effects
- fatigue
- headache
- abdominal pain
- diarrhea
- nausea
- pain or aches
- decreased appetite
- weight loss
- fever
In addition to medications, a person’s treatment team may recommend other types of treatment for small-cell lung cancer. Surgery or radiation may help with treating cancer and improving symptoms.
Surgery
The healthcare team will evaluate the location, size, and number of tumors to assess the appropriateness of surgery. If surgery has spread to other body areas, the healthcare team likely won’t recommend surgery.
For some people with small-cell lung cancer, their team may recommend surgery to remove the tumor and surrounding tissue. According to a
Radiation
Radiation therapy uses beams of intense energy to kill cancer cells and shrink tumors. According to a
When healthcare professionals recommend radiation therapy, the treatment plan typically includes radiation combined with surgery or chemotherapy.
Small-cell lung cancer carries a
With improvements in medical treatment, the overall survival rates of this type of cancer continue to improve.
Small-cell lung cancer occurs less frequently. However, it tends to cause a more aggressive form. Treatment plans often require a combination of multiple medications, surgery, or radiation.
Often, healthcare professionals recommend a combination of chemotherapy or immunotherapy recommendations to treat cancer.
Medications may include:
- etoposide
- cisplatin
- carboplatin
- irinotecan
- atezolizumab
- durvalumab