Some people use the term “type 3 diabetes” to describe Alzheimer’s disease. However, official health organizations do not accept this term, and most doctors do not use it for diagnostic purposes.

Although health associations do not classify type 3 as an official form of diabetes, insulin and glucose dysregulation makes it similar to other types, such as type 1 and type 2 diabetes. However, type 3 diabetes involves the brain and leads to Alzheimer’s disease.

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“Type 3 diabetes” is a term some people use to describe Alzheimer’s disease. Some scientists proposed the term because they believe insulin dysregulation in the brain causes dementia.

However, type 3 diabetes is not an officially recognized health condition. The American Diabetes Association and other major health organizations do not list Alzheimer’s disease as a type of diabetes within their classification.

Other types of diabetes include:

In addition, some research uses the term “type 3C” to classify pancreatogenic diabetes that may result from pancreatitis. This type is different from Alzheimer’s disease.

There are fundamental differences between type 3 diabetes (Alzheimer’s disease) and type 1 and type 2 diabetes. Alzheimer’s disease is an entirely separate condition.

In the following table, we compare diabetes types 1, 2, and 3.

Type 1 diabetesType 2 diabetesType 3 diabetes (Alzheimer’s disease)
What is happening?The body attacks the cells in the pancreas, which causes them to lose the ability to make insulin.The body does not use insulin well or cannot make enough to keep up with the demand.The body experiences impaired insulin and insulin-like growth factor signaling, oxidative stress, and inflammation.
Risk factors and causesScientists currently do not know the exact cause of type 1 diabetes, but genes or viruses may trigger it.Overweight, obesity, and physical inactivity may lead to type 2 diabetes.Possible risk factors are a lack of a balanced diet, obesity, type 2 diabetes, inactivity, genes, ethnicity, and high blood pressure.
Management Management involves insulin medications.Medication, diet, and exercise may help people with type 2 diabetes.Management of Alzheimer’s disease involves medications and support. People can manage blood sugar through diet and lifestyle.
Treatment and preventionThere is no cure, but medication can help manage the condition. Studies on prevention are ongoing.Lifestyle and dietary changes can help treat and prevent type 2 diabetes.Treatment of Alzheimer’s disease involves medication, although there is no cure. Physical activity, a nutritious diet, and a moderate body weight can help prevent insulin resistance.

Read on to learn more about the differences between type 1 and type 2 diabetes.

Doctors do not use “type 3 diabetes” as a diagnostic term because it is not an official classification. However, they can diagnose Alzheimer’s disease using physical and mental tests, neurological exams, and brain imaging.

According to the Alzheimer’s Association, the early signs and symptoms of Alzheimer’s disease include:

  • memory loss that negatively affects daily life
  • trouble resolving problems or making plans
  • difficulty carrying out familiar tasks
  • confusion about location or time
  • difficulty using and understanding written and spoken language
  • mislaying things
  • decreased judgment
  • withdrawal from social activities or work
  • mood and personality changes

It is important to note that some changes in memory and habits can be part of aging. However, if a person has concerns about any changes they are experiencing, they can seek guidance from a doctor.

Read on to learn more about the different stages of Alzheimer’s disease.

The term type 3 diabetes derives from the potential role of insulin and insulin resistance in the development of Alzheimer’s disease. Some researchers proposed this term due to the similar features present in diabetes, memory deficits, and a decline in thinking abilities in older adults.

Insulin helps control blood sugar levels by enabling glucose to enter cells. Additionally, it also affects metabolism, nerve cells, how neurons communicate, and thinking functions in the brain.

When a person develops insulin resistance, it can reduce the supply of glucose to the brain and can cause changes to tau, a protein involved in the development of dementia. Additionally, when the brain does not receive sufficient glucose, this can damage the brain and weaken the connection between brain regions.

A 2020 study lists the potential risk factors for developing type 3 diabetes. These include:

  • a diet high in calories, sugar, and fat and low in fiber
  • low socioeconomic status
  • exposure to stress
  • race and ethnicity
  • lack of physical activity
  • genetics
  • family history
  • birth weight

The same study indicates that high blood pressure and impaired lipid, or fat, transportation play a role in the development of Alzheimer’s disease. Additionally, having the APOE4 gene can increase a person’s risk of the condition.

Similarly, the Alzheimer’s Society notes that diabetes is a risk factor for developing dementia.

There is no cure for type 3 diabetes (Alzheimer’s disease), but doctors may prescribe drugs to slow the progression of the condition or treat its symptoms.

Changing disease progression

Aducanumab is an anti-amyloid antibody drug that may help reduce cognitive and functional decline in people in the early stages of Alzheimer’s disease.

Treating symptoms

Medications that can lessen memory loss and thinking issues in Alzheimer’s disease include donepezil and galantamine.

Drugs that may improve behavioral and psychological symptoms include suvorexant, which may help prevent insomnia.

Additionally, some people use alternative and natural treatments. However, the Alzheimer’s Association notes that these may not be effective or safe.

The National Institute on Aging states there is encouraging, though inconclusive evidence that the following may help prevent or delay type 3 diabetes (Alzheimer’s disease) and cognitive decline:

There is also no definite evidence concerning dietary therapies for Alzheimer’s disease prevention.

Some research has explored curcumin, a ketogenic diet, and antioxidants as potential therapeutic agents, but studies have been inconclusive so far.

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) advises that reaching or maintaining moderate body weight and engaging in enough physical activity may help prevent insulin resistance and prediabetes.

Although scientists have not proven the effectiveness of any strategies for avoiding Alzheimer’s disease, managing blood sugar may be a sensible approach.

A doctor may also prescribe metformin to delay the onset of or treat diabetes.

Read on to learn more about the symptoms of early onset Alzheimer’s disease.

There is no cure for type 3 diabetes (Alzheimer’s disease). However, there are many treatment options available that may lessen the severity of symptoms and prolong a person’s life.

Some people with Alzheimer’s disease will not develop symptoms for years, although this can vary from person to person.

Most people with Alzheimer’s disease will die from another cause. However, since the disease causes neurological problems, it could lead to:

People with Alzheimer’s disease may require palliative care to improve their quality of life in the final stages of the condition.

“Type 3 diabetes” is a term some people use to describe Alzheimer’s disease, but major health organizations do not recognize it as a type of diabetes in their classifications.

Scientists believe that insulin resistance in the brain can lead to the characteristic symptoms of Alzheimer’s disease, such as amyloid plaques, oxidative stress, and inflammation.

While researchers have called for more studies, they acknowledge that some factors seem to increase the risk of developing Alzheimer’s disease. These include overweight, little physical activity, and high blood pressure.

People can use diet and lifestyle changes to manage their weight and blood sugar, which may play a role in preventing cognitive decline.