Several blood thinners are available to prevent stroke in people with atrial fibrillation (AFib). The safest blood thinner for a person depends on their medical conditions and overall health.
One of the main focuses of AFib treatment is to reduce the likelihood of stroke by preventing the formation of blood clots. Blood thinners can decrease the rate of AFib-related stroke by
Until the last decade, warfarin was the only drug approved by the Food and Drug Administration (FDA). Newer blood thinners are now available to prevent stroke in people with AFib.
This article explores blood thinners doctors may prescribe for AFib and their possible side effects. It also explores other potential treatments doctors may use to treat AFib.
Certain blood thinners may be
Vitamin K antagonists
However, warfarin has a
- eating green leafy vegetables and fruits, such as kiwi and avocado
- taking medications
- having certain genetic mutations
New oral anticoagulants (NOACs)
- Direct thrombin inhibitors: These medications block the action of thrombin, an essential component in blood clot formation. Examples include dabigatran, bivalirudin, and argatroban.
- Factor Xa inhibitors: These bind directly to factor Xa, the protein responsible for creating thrombin, inhibiting it from making thrombin. Examples of these medications are rivaroxaban, edoxaban, betrixaban, and apixaban.
People may also refer to NOACs as direct oral anticoagulants (DOACs) and target-specific oral anticoagulants (TSOACs).
The 2019 guidelines by the American College of Cardiology (ACC) and the American Heart Association (AHA) recommend NOACs over warfarin, although NOACs are not suitable for everyone.
Some research indicates that newer anticoagulants
- fewer drug interactions
- rapid onset, eliminating the need to bridge with another medication that is necessary with warfarin
- potential freedom from periodic blood test monitoring
- clears from the body quicker than warfarin
These drugs also
A person should speak with a healthcare professional to determine which blood thinner may be best for them or if an alternative treatment may be more appropriate.
The drugs discussed in the section above carry a
For example, a
Other person-related factors
- underlying medical conditions
- coagulopathy, which affects how the body manages blood clotting
- recent surgery
A person taking warfarin requires
In cases of significant and life threatening bleeding, all these medications have reversal agents to counteract their effects.
A healthcare professional will consider if the benefits of a blood thinner outweigh its risks before deciding whether to prescribe it on an individual basis.
They may also give medications or other treatment for underlying conditions that reduce a person’s risk factors for AFib. Some of these medications aim to address the following:
Doctors typically prescribe medications and lifestyle changes that may help prevent further complications associated with Afib. These include:
- maintaining a moderate weight
- being physically active
- limiting alcohol and stimulants such as caffeine
- seeking support to address substance use
- quitting smoking
- managing stress
- following a healthy diet
A healthcare professional may also consider medical procedures and surgery when medications and lifestyle changes fail to address a person’s AFib symptoms. These treatment options may include:
Several blood thinners help prevent strokes and blood clots in people with atrial fibrillation. However, these drugs come with risks and side effects, which doctors discuss with people before starting treatment.
In addition to medications, a healthcare professional may also recommend lifestyle changes and procedures or surgery depending on the severity of a person’s AFib.
A person should speak with a doctor who will consider factors such as age, overall health, and existing health conditions when determining the most suitable treatments for them.