We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission. Here’s our process.

Is CBD legal?The 2018 Farm Bill removed hemp from the legal definition of marijuana in the Controlled Substances Act. This made some hemp-derived CBD products with less than 0.3 percent THC federally legal. However, CBD products containing more than 0.3 percent THC still fall under the legal definition of marijuana, making them federally illegal but legal under some state laws. Be sure to check state laws, especially when traveling. Also, keep in mind that the FDA has not approved nonprescription CBD products, and some products may be inaccurately labeled.

CBD, or cannabidiol, is a chemical compound and one of several cannabinoids present in the cannabis Sativa plant. CBD is available in many forms, including oils. Some of the most potent oils contain up to 12,000 mg of CBD per 30 ml.

CBD has become a popular ingredient in oils, edibles, topicals, and cosmetics. CBD does not cause the ‘high’ typically associated with cannabis use. The cause of the ‘high’ is another cannabinoid called tetrahydrocannabinol (THC).

People curious about CBD products may wonder about the most potent CBD oil available.

This article provides a list of high-potency CBD oils and other CBD products. We also discuss the potential benefits and risks of using strong CBD.

Read our complete CBD buyer’s guide here

Medical News Today chooses products that meet the following criteria:

  • Ingredients: MNT chooses products containing safe and high quality clearly labeled ingredients. They should also confirm they are free from pesticides, heavy metals, and mold.
  • Dosage: MNT chooses products that must clearly state the CBD dosage.
  • Serving size: MNT selects products in which manufacturers recommend a dosage.
  • Third-party labs: MNT chooses products that must undergo third-party testing for contaminants by an ISO 17025-compliant laboratory.
  • Available certificate of analysis: MNT chooses companies that demonstrate transparency and share a product’s certificate of analysis (COA) after receiving its third-party lab results.

Below are some examples of high-strength CBD oils and tinctures. Oils and tinctures undergo slightly different extraction processes. Manufacturers produce CBD oils by using carbon dioxide to extract CBD. They use alcohol to manufacture tinctures.

Learn more about CBD tinctures here.

Please note that this article’s writer has not tried these products, and all the information presented is research-based.

Medical News Today follows a strict product selection and vetting process. Learn more here.

Best overall: Zatural Full Spectrum CBD Oil Drops

Zatural Broad Spectrum CBD Oil Drops contain hemp seed oil with no additives or fillers. The oil also contains terpenes, flavonoids, and phytocannabinoids.

The company states the product is THC-free.

This product is available in 1, 2, and 4 fluid ounce (fl oz) bottles, containing 300–12,000 milligrams (mg) of CBD.

The 12,000 mg option provides a CBD dosage of 100 mg per serving, making it one of the strongest CBD oils in this article.

  • Pros: no additives or fillers, range of potency options, organic
  • Cons: more expensive than other options

The strongest dosage option costs between $112-360, depending on the bottle size.

Learn more about Zaturals here.

Strongest per serving: CBDMD CBD Oil Tincture Drops

CBDMD’s CBD Oil Tincture Drops contain 7,500 mg of broad-spectrum CBD per 1 fl oz bottle. The oil provides 250 mg of CBD per serving, the strongest dose in this article.

It contains additional cannabinoids, including cannabinol (CBN) and Cannabigerol (CBG). It is also made with MCT oil.

This CBD oil is vegan and free from THC and gluten.

This tincture comes in natural, mint, orange, or berry flavors.

  • Pros: THC-free, multiple flavors, vegan
  • Cons: high dose may not suit everyone

A 1-ounce bottle costs $209.99.

Use code HEALTHLINE for 20% off all orders.

Learn more about CBDMD here.

Best for quality: Spruce Lab Grade CBD Oil

Spruce’s 2,400 mg full-spectrum CBD Oil delivers 80 mg of full-spectrum CBD per 1 milliliter (ml) dose, equivalent to a full dropper.

The oil is organic and contains no added flavoring. The carrier oil is hemp seed oil, and the product is also vegan and gluten-free.

This product contains 0.3% THC. The company states that a person taking it might test positive for cannabis, which is unsuitable for people undergoing drug testing.

  • Pros: organic, vegan, and free from gluten, pesticide, preservatives, and artificial flavors
  • Cons: more expensive than other options, contains THC, so unsuitable for drug testing.

A 1 oz bottle costs $269.

Use code “MNT” for 15% off and free shipping.

Best for travel: NuLeaf Naturals Full Spectrum Hemp CBD Oil

NuLeaf Naturals offers a full-spectrum CBD oil available in a range of bottle sizes and dosages, from 300-6,000 mg.

The range of bottle sizes may make this product suitable for travel.

The company suggests that people start by using 30 mg or 10 drops each day in two separate doses. They may then increase the dose slowly if needed.

NuLeaf Naturals use full-spectrum CBD and organic hemp seed oil to produce CBD oil products.

The product is unflavored and contains terpenes.

People can also buy a single bottle or buy packs of 3 or 6 bottles.

  • Pros: organic, bulk buy options available, smaller bottles available
  • Cons: no flavor options, lower dosage than other products

NuLeaf Naturals Full Spectrum Hemp CBD Oil costs between $15.20-119.20, depending on the bottle size.

Best for adjusting dosage: MyNaturalCBD Full Spectrum CBD Oil Tincture

This full-spectrum CBD Oil from MyNatural CBD contains about 167 mg of CBD per ml and about 8.2 mg of CBD per drop. People can adjust how many drops they take as needed.

MyNatural CBD also offers CBD oils in 300, 1,000, and 2,500 mg strengths.

Each bottle contains two ingredients: premium CBD oil from hemp and MCT oil from coconuts.

The product is organic, non-GMO, and gluten-free.

The company states the product contains less than 0.3% THC.

  • Pros: simple ingredients, organic, gluten-free
  • Cons: high cost compared with other products in this list, contains THC

A 1-ounce bottle costs $379.

Best hemp and CBD oil: Green Gorilla Organic Full Spectrum CBD Oil

This reportedly potent, fast-acting, full-spectrum, certified organic product contains 3,000 mg of hemp extract and 600 mg of active CBD oil per bottle. It may contain up to 0.3% THC.

Each dose contains 20 mg of hemp extract and 5 mg of active cannabidiol.

There are phytocannabinoids, terpenes, and flavonoids in each dose. The product includes all parts of the hemp plant.

Green Gorilla recommends that people start by using five pumps of the 3,000 mg hemp oil per day, then increase or decrease the dosage based on how they feel.

  • Pros: organic, free from dyes, additives, and preservatives
  • Cons: no flavors

A 2 fl oz bottle costs. $74.99.

The table below provides a quick comparison of the strongest CBD oils in this article:

PriceSizeDosage per bottleDosage per serving
Zatural$112-3601, 2, and 4 fl oz12,000 mg100 mg
CBDMD$209.991 fl oz7,500 mg250 mg
Spruce$2691 oz2,400 mg80 mg
NuLeaf$15.20-119.200.17-3.38 fl oz300-6,000 mg30 mg
MyNaturalCBD$3791 oz5,000 mg8.2 mg
Green Gorilla$74.992 fl oz3,000 mg25 mg

A person interested in trying CBD oil should research different products to find one that is safe and reliable. Customer reviews from third-party sites such as the Better Business Bureau and Trustpilot are useful tools when researching brands.

A person may want to review each product’s ingredient list and concentration levels. They might want to know if the product is lab-grade and third-party tested.

A person using CBD for the first time may find a product with a lower dosage more suitable. They can then gradually increase the dosage as desired.

While there is a wealth of research regarding the effects of cannabis and THC, there are few high quality human trials investigate CBD alone.

It is difficult for experts to predict precisely how differences in strength impact CBD’s effectiveness.

Based on the findings of a 2020 review, CBD appears relatively safe at various doses. However, the authors did not pinpoint a specific dose or range of doses they believed would benefit everyone.

Most of the studies included in this review evaluated daily doses of 300–600 mg of CBD, but a few studies reported using doses as high as 2,000 mg per day.

Everyone responds differently to CBD, so it is best for people using CBD for the first time to start at a lower dose.

Purchasing a higher CBD concentration product may be more cost-effective and convenient for some people.

For example, someone who uses 300 mg of CBD for chronic pain or anxiety would use 12 full droppers of 25 mg CBD oil. They could get a similar 300 mg dose by using only one and a half droppers of 2,000 mg CBD oil.

However, stronger products may provide more CBD per unit but may lead to inaccurate dosing.

Learn more about CBD dosage here.

CBD does not appear to cause any significant side effects, even at doses above 150 mg per kilogram (kg) of body weight.

However, the Food and Drug Administration FDA warns that using CBD products may produce the following adverse effects:

  • drowsiness
  • gastrointestinal problems
  • diarrhea
  • decreased appetite
  • mood changes, such as irritability
  • liver injury (with certain drug interactions)
  • interactions with alcohol and other drugs

The FDA has approved only one CBD product called Epidiolex for severe forms of childhood epilepsy. The FDA does not regulate any other CBD products.

Learn more about the side effects of CBD here.

Label accuracy

In a 2017 study, researchers evaluated the label accuracy of 54 CBD products from 31 companies. They tested various products, including oils, tinctures, and vaping formulas. Their third-party laboratory analysis showed that 30.95% of product labels had accurate CBD concentrations.

According to the authors, CBD oils had more accurate labeling than tinctures and vaping formulas.

However, most reputable CBD manufacturers will provide third-party lab results to their customers.

People should always use caution when shopping for CBD, especially high potency products. High-potency CBD products can be inaccurately labeled. Some products may not even contain CBD.

Additionally, some CBD products may contain enough THC to produce a positive result in a drug test.

Learn more about THC and drug tests here.

A person should always speak with their healthcare professional before trying any supplement, including CBD oil, especially if they are currently taking medications.

Research suggests that CBD may interact with some medications.

Below are some of the most commonly asked questions about CBD oils.

When is the best time to take CBD oil?

There is no best time to take CBD oil. Some companies suggest people take doses of their CBD oil products more than once during the day. However, some people may find that CBD oil makes them drowsy, making it suitable for bedtime use.

Is it safe to take CBD oil daily?

Current research has not indicated any negative impacts of taking CBD oil daily. Additionally, many companies that manufacture these products recommend that people take a daily dose of CBD oil.

How do I determine what dose of CBD oil is best for me?

People taking CBD oil who feel they may benefit from taking more can slowly increase their dosage and gauge the results. Those who have never used CBD oil should start with a lower dose and gradually work up to a stronger dose.

CBD is a popular product. Current preliminary research suggests CBD may be beneficial for treating various conditions, including epilepsy, anxiety, and some forms of chronic pain.

Learn more about the potential benefits of CBD oil here.

However, more high quality, controlled trials are needed to verify the medical applications of CBD.

People who currently use CBD products but feel they may benefit from stronger alternatives can use this article for guidance. People who have never used CBD but are interested in giving it a try should start with a low dose and gradually work their way up to more potent products.

People should also discuss CBD with a doctor, as it might interact with medications and supplements.

Learn more about cannabinoids and possible drug interactions here.