Creating a free account will enable you to subscribe to our daily and weekly email newsletters, as well as customize your reading experience to show only the categories most relevant to you.
Signing up only take a few minutes, so why not give it a try and see what you've been missing out on.
Researchers say they have uncovered the first evidence that nerves situated in the stomach follow a circadian rhythm and limit a person's food intake to certain times throughout the day. This is according to a study published in The Journal of Neuroscience.
Investigators from the University of Adelaide in Australia say their findings may lead to insight into how the stomach tells the brain we are hungry or full.
To reach their findings, the researchers analyzed 8-week-old mice to determine how nerves in the stomach respond to "stretch" - a process that occurs following food intake at 3-hourly intervals throughout the day.
According to Dr. Stephen Kentish, of the University of Adelaide's Nerve-Gut Research Laboratory, these nerves are responsible for telling the brain how much food a person has eaten, and when to stop eating.
But their study found that the nerves in the gut have minimal sensitivity during times of the day that are associated with being awake.
"This means more food can be consumed before we feel full at times of high activity, when more energy is required," Dr. Kentish explains.
"However, with a change in the day-night cycle to a period associated with sleeping, the nerves in the stomach become more sensitive to stretch, signaling fullness to the brain quicker and thus limiting food intake.
This variation repeats every 24 hours in a circadian manner, with the nerves acting as a clock to coordinate food intake with energy requirements."
Although this study was conducted in mice, the investigators believe the same process applies to the human body.
"Our theory is that the same variations in nerve responses exist in human stomachs, with the gut nerves being less sensitive to fullness during the day and more sensitive at night," says Dr. Kentish.
The researchers say their findings could lead to to discoveries regarding how people's eating habits could be affected by changes in their circadian clock.
Associate Prof. Amanda Page, of the University of Adelaide and leader of the study, uses the example of shift workers, who are more likely to experience sleep disruptions and irregular eating habits.
Previous research has suggested that nurses who work long shifts, overtime or other adverse work schedules may be more prone to obesity.
The investigators say they are now conducting further research to see how changes to the circadian rhythm impacts eating behavior, and how the nerves in the stomach react to the changes.
Medical News Today recently reported on a study suggesting that a "hunger gene" called KSR2 may be responsible for hunger pangs in individuals who are obese.
Written by Honor Whiteman
Copyright: Medical News Today
Not to be reproduced without the permission of Medical News Today.
Circadian Variation in Gastric Vagal Afferent Mechanosensitivity, doi: 10.1523/JNEUROSCI.3846-13.2013, Stephen J. Kentish, Claudine L. Frisby, David J. Kennaway, Gary A. Wittert, Amanda J. Page, published in The Journal of Neuroscience, 4 December 2013. Abstract
Stomach 'clock' tells us how much to eat, news release from the University of Adelaide, accessed 6 December 2013.
Visit our Neurology / Neuroscience category page for the latest news on this subject.
Please use one of the following formats to cite this article in your essay, paper or report:
Whiteman, Honor. "'Stomach clock' limits food intake to specific times, study suggests." Medical News Today. MediLexicon, Intl., 9 Dec. 2013. Web.
24 Apr. 2014. <http://www.medicalnewstoday.com/articles/269799>
Whiteman, H. (2013, December 9). "'Stomach clock' limits food intake to specific times, study suggests." Medical News Today. Retrieved from
Please note: If no author information is provided, the source is cited instead.
For any corrections of factual information, or to contact our editorial team, please use our feedback form. Please send any medical news or health news press releases to:
Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.
This page was printed from: http://www.medicalnewstoday.com/articles/269799.php
Visit www.medicalnewstoday.com for medical news and health news headlines posted throughout the day, every day.
© 2004-2014 All rights reserved. MNT is the registered trade mark of MediLexicon International Limited.