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Magnesium glycinate is a supplement that increases magnesium levels. Magnesium is essential for managing blood pressure and other functions. People with a magnesium deficiency may benefit from supplements, but not everyone will need them.

Magnesium is a vital nutrient for regulating many body processes, including muscle and nerve function, blood sugar levels, and blood pressure. This mineral also supports the making of protein, bone, and DNA.

The body requires magnesium in large amounts. This type of mineral is known as a macro-mineral.

While the most efficient way to consume nutrients is in their natural forms, supplements are available to boost magnesium intake in people with low levels.

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Magnesium glycinate is a supplement that the body can easily absorb.

People often use magnesium glycinate instead of other magnesium supplements, as the body finds it easier to absorb magnesium in this form. It is also one of the gentlest supplements on the stomach.

Unlike other forms of magnesium, it might not cause as many side effects, such as an upset stomach or loose stools.

This characteristic makes magnesium glycinate a good supplement for people recovering from bariatric surgery or anyone who might be at risk for magnesium levels.

People who have kidney issues should consult a doctor before taking magnesium glycinate. Kidney problems can cause difficulties in excreting the excess magnesium.

Some people benefit more from magnesium glycinate than others.

People with the following conditions might see positive effects after taking magnesium glycinate:

  • High blood pressure or heart disease: Magnesium supplements can help decrease blood pressure slightly.
  • Type 2 diabetes: Consuming high amounts of magnesium in the diet might reduce the risk of type 2 diabetes. Magnesium helps to break down sugars and might decrease insulin resistance.
  • Osteoporosis: Magnesium plays a role in the development of healthy bones, and people with higher levels of magnesium might have a higher bone mineral density. This is important in helping reduce the risk of bone fractures and osteoporosis.
  • Migraine headaches: People who experience migraines sometimes have low levels of magnesium in their blood and tissues. Supplements may help reduce the frequency of migraines.
  • Depression: Serotonin is a “feel-good” chemical in the brain. Insufficient levels of magnesium seem to reduce serotonin levels, and antidepressants can raise levels of brain magnesium.

Measuring magnesium levels in the blood can show misleading results because magnesium sits within the cells or bones, rather than the bloodstream.

Doctors will typically measure serum magnesium concentrations in the blood, saliva, or urine to help assess levels as accurately as possible.

A person should wait for a final diagnosis of deficiency before taking supplements, as the symptoms commonly associated with low magnesium levels could be the cause of another health problem.

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Legumes are a key source of magnesium.

Most people can reach the recommended daily dosage through diet alone.Many common foods contain magnesium.

Common foods that contain magnesium include:

  • legumes, nuts, and seeds
  • whole grains
  • spinach and other leafy vegetables
  • fortified breakfast cereals and other fortified foods
  • yogurt, milk, and other dairy products

Magnesium glycinate supplements are available to purchase online. Click here for an excellent range with thousands of customer reviews.

Speak to a doctor before taking any new supplements.

The recommended daily amount of magnesium depends on the age and sex of a person. The National Institutes of Health (NIH) provide guidelines for the daily recommended amount in milligrams (mg) below.

Between birth and 6 months30 mg
Infants 7 to 12 months75 mg
Children aged 1 to 3 years80 mg
Children aged 4 to 8 years130 mg
Children aged 9 to 13 years240 mg
Boys ages 14 to 18 years410 mg
Girls ages 14 to 18 years360 mg
Adult men400 to 420 mg
Adult women310 to 320 mg
Pregnant teens400 mg
Pregnant women350 to 360 mg
Breast-feeding teens360 mg
Breast-feeding women310 to 320 mg

According to the NIH, most people in the United States do not get enough magnesium from their daily diet. Men older than 70 years of age and girls under 18 years of age are most likely to have low intakes of magnesium.

Low magnesium intake does not typically cause any symptoms. The body loses a certain amount of magnesium every day as a result of normal processes, such as muscle movement, the heartbeat, and hormone production.

Though only a person needs only a small amount of magnesium, it is important to replenish magnesium levels to prevent deficiency.

When people who do not have magnesium deficiency experience low magnesium levels, the kidneys help to retain magnesium by restricting the amount that the body loses in the urine. This process has a temporary effect until levels rise, but a person with low magnesium levels for long periods can develop magnesium deficiency.


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Some gastrointestinal diseases can lead to magnesium deficiency.

There are non-dietary causes that can reduce magnesium levels.

Some medical conditions and medications affect magnesium absorption. They can also increase the amount of magnesium expelled from the body. These factors can result in magnesium deficiency.

Health conditions that can lead to magnesium deficiencies include:

Some medications can have a similar effect, including:

  • taking prescription drugs used to treat acid reflux or peptic ulcers, which can lead to low blood levels of magnesium when people take them over a long period
  • taking diuretics, which assist with water retention and can increase or decrease the loss of magnesium through urine.

Certain lifestyle factors can also reduce magnesium levels, including:


People who are deficient in magnesium can experience the following symptoms:

  • loss of appetite
  • nausea
  • vomiting
  • fatigue and weakness

Extreme magnesium deficiency can lead to the following symptoms:

  • tingling
  • numbness
  • muscle cramps
  • seizures
  • personality changes
  • abnormal heart rhythm

Only a doctor should diagnose magnesium deficiency.

They can confirm the condition through blood tests, as well as identify the correct plan of action to return magnesium levels to normal.

Taking large or frequent doses of dietary magnesium supplements, including magnesium glycinate, can cause adverse effects, including diarrhea, nausea, and stomach cramps. Extremely high intakes of magnesium can lead to an irregular heartbeat and potentially a cardiac arrest, which can be dangerous.

Magnesium glycinate and other supplements might also interfere or interact with the following medicines:

  • Bisphosphonates: These are used to treat osteoporosis. The body does not absorb these drugs well if people take them too close to taking supplements or medications that contain a high amount of magnesium.
  • Antibiotics: The body may not absorb some antibiotics if an individual takes them too soon before or after a magnesium supplement.

Taking extremely high doses of supplemental zinc can also interfere with the absorption and regulation of magnesium in the body.


Which other nutrients are vital?


Thirteen nutritional vitamins are essential for supporting health.

These include the B vitamins, such as niacin, riboflavin, thiamine, biotin, pantothenic acid, B-6, B-12, and folate, along with vitamins A, C, D, E, and K. Adequate calcium and potassium intake is also important.

Alan Carter, PharmD Answers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.

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