A new study links chronic insomnia with kidney decline and failure, as well as with the risk of early death in the case of United States veterans. Managing long-term sleeplessness may help to stave off such negative health outcomes, the researchers hypothesize.
Research has identified insomnia as the
Sleeplessness is also linked with a large number of health conditions, including depressive symptoms, attention deficit hyperactivity disorder (ADHD), and Alzheimer's, to name but a few. On the flip side, recent studies have emphasized the protective quality of a good night's sleep when it comes to the chronic effects of stress.
A recent study from the University of Tennessee Health Science Center in Memphis, TN, now links insomnia with kidney function decline, kidney failure, and an increased mortality risk.
Drs. Csaba Kovesdy and Jun Ling Lu, the lead researchers involved with the study, focused on the risks posed by chronic insomnia to kidney health, and for this purpose they worked with a large cohort of U.S. veterans.
Insomnia raises risk of kidney disease
The researchers studied renal health and all-cause mortality outcomes for a nationwide group of 957,587 veterans with no kidney-related health issues at baseline. Of these, 41,928 participants had chronic insomnia.
During a median follow-up period of 6.1 years, 23.1 percent of the study participants died, while 2.7 percent exhibited an accelerated decline of kidney function. Also, 0.2 percent of the participants had kidney failure.
The researchers noted that chronic insomnia was tied to a 1.4 times higher risk of mortality for any cause, as well as a 1.5 times higher risk of kidney decline, and an even steeper increase in risk of kidney failure: 2.4 times.
These results indicate that consistent sleeplessness could play a role in the development of chronic kidney disease (CKD), as well as shorten life expectancy overall.
'Long-ranging positive effects' of sleep
According to data from the National Institute of Diabetes and Digestive and Kidney Diseases, the prevalence of CKD in the overall U.S. population is of approximately 14 percent.
Dr. Kovesdy and team suggest that their study's findings should lead to more attentive management of insomnia, as this might have wider reaching benefits in the long run, and help prevent the development of other chronic health conditions, such as CKD.
"Chronic insomnia is an important and relatively common condition among patients with normal kidney function. Attention to its proper management could have long-ranging positive effects."
Dr. Csaba Kovesdy
However, the researchers acknowledge that more in-depth studies are needed to confirm how effective actions targeting chronic insomnia would be in keeping other health conditions at bay.
"This hypothesis will need to be examined in dedicated prospective studies, including clinical trials," says Dr. Kovesdy.