Entyvio (vedolizumab) is a brand-name prescription drug. The Food and Drug Administration (FDA) has approved it to treat certain types of inflammatory bowel disease in adults. These include moderate to severe Crohn’s disease and ulcerative colitis.

For more information about Entyvio’s uses, refer to this article.

Drug details

Here are some details about Entyvio, which is a biologic:

  • How it’s given: IV infusion by a doctor or another healthcare professional
  • Biosimilar version: none available

Read on to learn about Entyvio and its cost, as well as how to save money on prescriptions.

As with all drugs, the cost of Entyvio can vary. Factors that may affect the price you’ll pay include:

  • your treatment plan
  • your insurance coverage
  • the cost of the visit to your doctor to receive doses of Entyvio
  • whether Entyvio has a savings program (see the “Financial and insurance assistance” section below)

To find out what the cost of Entyvio will be for you, talk with your doctor, or insurance provider.

Insurance considerations

Below is information you may want to consider if you have insurance and receive Entyvio.

Prior authorization. If you have insurance, your insurance company may require prior authorization before it covers Entyvio. This means the company and your doctor will discuss Entyvio in regard to your treatment. The insurance company will then determine whether the medication is covered. If a drug requires prior authorization but you start treatment without prior approval, you could pay the full cost of the medication. You can ask your insurance company whether Entyvio requires prior authorization.

Type of insurance coverage. Entyvio is given by your doctor or another healthcare professional. If you have insurance, the price of your Entyvio doses may be billed through your primary health insurance instead of the prescription drug portion of your insurance. This depends on your insurance coverage and where you receive your Entyvio doses, such as at your doctor’s office, an infusion clinic, or a hospital. If you have questions about this process, contact your doctor or your insurance provider.

Here are answers to some frequently asked questions about drug cost and Entyvio.

What are the costs of Entyvio with and without insurance coverage?

The costs of Entyvio with and without insurance depend on various factors. These include:

  • your insurance plan, if you have one
  • where you get your Entyvio infusion, such as a clinic or doctor’s office
  • if you qualify for Entyvio savings programs
  • your treatment plan

In general, the cost of Entyvio with insurance may be less than the cost without insurance. To find out the exact cost of Entyvio to treat your condition, talk with your doctor, or insurance provider. You can also refer to the “Financial and insurance assistance” section below to find out about cost savings programs.

Is there a copay card for Entyvio?

Yes, there’s a copay card available for Entyvio. It’s called the EntyvioConnect copay card savings program. If you have private health insurance, you may be eligible for this copay card. For more information and to find out if you’re eligible for support, call 855-368-9846 or visit the program website.

If you don’t have insurance or you have government insurance, you may be eligible for other cost savings programs. To learn more, see the “Financial and insurance assistance” section below.

How can I figure out Entyvio’s cost per 300-mg infusion?

Entyvio’s cost per 300-milligram (mg) IV infusion depends on whether you have insurance or are paying out of pocket. It also varies based on other factors. For example, you may have to pay a separate fee to receive Entyvio infusion at a clinic or doctor’s office. This cost would be in addition to the Entyvio injection price.

Entyvio’s cost per 300-mg infusion may vary based on your insurance plan benefits and your copay. Your cost may also depend on whether you qualify for any Entyvio cost savings programs. To learn more, see the “Financial and insurance assistance” section below.

To learn how much you can expect to pay for Entyvio infusion, talk with your doctor or insurance provider.

If I have Medicare, what is the cost of Entyvio?

If you have Medicare, the cost of Entyvio depends on your individual plan coverage and benefits. Your cost also varies based on copays and your Medicare deductible.

Different parts of Medicare may cover portions of the cost of Entyvio. For example, if you have a Part D plan, it may cover the Entyvio injection price. If you have Medicare Part B, it may cover your visit to your doctor’s office or clinic where you receive your infusion.

To find out the cost of Entyvio based on the Medicare plan you have, call your plan provider for details. You can also learn more about Medicare plans in the “Next Steps” section below.

If you need financial support to pay for Entyvio, or if you need help understanding your insurance coverage, help is available. For example:

  • A program called EntyvioConnect copay card is available for Entyvio for those with private health insurance. To learn more about the program and to find out if you’re eligible for support, call 855-368-9846 or visit the program website. For more information about the program, you can also view “Is there a copay card for Entyvio?” in the “Common questions about cost and Entyvio” section above.
  • Some websites provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services. Two such websites are:

To learn more about saving money on prescriptions with or without insurance, check out this article.

Entyvio contains the active ingredient vedolizumab, and it’s available only as a brand-name biologic drug. It doesn’t come in a biosimilar version. A biosimilar medication is a drug that’s similar to the brand-name biologic drug (Entyvio). Also, biosimilars tend to cost less than brand-name medications.


Biologic drugs can be expensive because of the research needed to test their safety and effectiveness. The manufacturer of a biologic drug can sell it for up to 12 years. When the biologic drug’s patent expires, multiple manufacturers can create biosimilar versions. This marketplace competition may lead to lower costs for biosimilars. Also, because biosimilars are very similar to biologic drugs, they don’t require the same costly testing.

Now that you’ve learned about cost factors and Entyvio, you may still have some questions. Talk with your doctor, who can provide personalized guidance about cost issues related to Entyvio. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you would pay for Entyvio.

Here are some other resources you may find helpful:

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.