Nexletol (bempedoic acid) is a brand-name drug prescribed to lower LDL cholesterol in certain adults, along with diet changes and a statin drug. Nexletol comes as an oral tablet that’s typically taken once per day.

Nexletol belongs to a drug class called adenosine triphosphate-citrate lyase inhibitors. Nexletol isn’t available in a generic version.

Keep reading for specific information about the dosage of Nexletol, including its strength and how to take the medication. For a comprehensive look at Nexletol, see this article.

Note: This article describes the typical dosage for Nexletol provided by the drug’s manufacturer. When taking Nexletol, always follow the dosage prescribed by your doctor.

The recommended dosage for Nexletol and other details about the drug are below.

Nexletol form

Nexletol comes as an oral tablet.

Nexletol strength

Nexletol is available in one strength of 180 milligrams (mg).

Typical dosage

The following information describes the dosage that’s commonly prescribed or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Dosage for lowering LDL cholesterol

Nexletol is prescribed to lower low-density lipoprotein (LDL) cholesterol in adults with heart disease or heterozygous familial hypercholesterolemia. Note that doctors prescribe Nexletol along with a statin* and diet changes.

The recommended dosage for lowering LDL cholesterol is one tablet (180 mg) once per day.

* Nexletol can affect how certain statin drugs work in your body. When you start Nexletol, your doctor may adjust your statin dosage to help reduce the risk of the statin’s side effects.

Long-term treatment

Nexletol is meant to be a long-term treatment. If you and your doctor determine that Nexletol is safe and effective for you, you’ll likely take it long term.

Nexletol comes as a tablet that you take once per day, with or without food. You may take Nexletol at any time of day, but it may be helpful to take it around the same time each day.

If you have trouble swallowing tablets, see this article for tips on how to take this form of medication. You can also talk with your doctor or pharmacist


Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.

If you’re having trouble opening medication bottles, ask your pharmacist about putting Nexletol in an easy-open container. They also may recommend tools that can make it easier to open bottles.

If you miss a dose of Nexletol, take the missed dose as soon as possible. However, if it’s almost time for your next dose, skip your missed dose. Then continue taking your next dose at your usual time. You should not take extra doses to make up for a missed dose.

To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or putting a note where you’ll see it, such as on your bathroom mirror or bedside table. You could also download a reminder app on your phone.

It’s important that you do not take more Nexletol than your doctor prescribes. For some medications, taking more than the recommended amount may lead to harmful effects or overdose. To learn about side effects of Nexletol, see this article.

If you take more than the recommended amount of Nexletol

Call your doctor right away if you believe you’ve taken too much Nexletol. Another option is to call America’s Poison Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

The dosage in this article is the typical dosage from the drug’s manufacturer. If your doctor recommends Nexletol for you, they’ll prescribe the dosage that’s right for you. Always follow the dosage that your doctor prescribes.

As with any drug, never change your dosage of Nexletol without your doctor’s recommendation. If you have questions about the dosage of Nexletol that’s best for you, talk with your doctor.

Besides learning about dosage, you may want other information about Nexletol. These additional articles might be helpful:

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.