Zomig (zolmitriptan) is a brand-name drug that’s prescribed for treating migraine episodes in adults and certain children. Zomig is available in three forms. It’s typically taken at the first sign of a migraine attack.
Zomig comes as an oral tablet, an orally disintegrating tablet, and a nasal spray. (The orally disintegrating tablet dissolves on your tongue. This form of Zomig is available under the name Zomig-ZMT.)
Zomig belongs to a drug class called triptans. All forms of Zomig are available in a generic version.
Keep reading for specific information about the dosage of Zomig, including its strengths and how to take the medication. For a comprehensive look at Zomig, see this article.
Note: This article describes typical dosages for Zomig provided by the drug’s manufacturer. When taking Zomig, always follow the dosage prescribed by your doctor.
Below is important information about Zomig dosage for its approved uses. Your doctor will determine the dosage that’s best for you.
Dosage summary
The following chart summarizes Zomig’s dosage. Milligrams is abbreviated as mg. Additional details about the dosage for this drug follow.
| Zomig form | Typical starting dose | Maximum single dose | Maximum daily dose |
| oral tablet | 1.25 mg or 2.5 mg | 5 mg | 10 mg |
| orally disintegrating tablet | 1.25 mg or 2.5 mg | 5 mg | 10 mg |
| nasal spray | 2.5 mg | 5 mg | 10 mg |
Zomig forms
Zomig comes in three forms:
- an oral tablet
- an orally disintegrating tablet (Zomig-ZMT)
- a nasal spray
Zomig strengths
Zomig comes in two strengths: 2.5 milligrams (mg) and 5 mg.
Typical dosages
Typically, your doctor will start you on a low dosage. Then they’ll adjust it over time to reach the amount that’s right for you. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect.
The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.
Dosage for migraine
Zomig’s starting oral tablet dosage is 1.25 mg or 2.5 mg. If your doctor recommends a 1.25-mg dose, you’ll split a 2.5-mg Zomig oral tablet in half.
However, the Zomig orally disintegrating tablet (Zomig-ZMT) should be taken whole. You should not split this tablet in half. (If your dosage is 1.25 mg, your doctor will likely not prescribe Zomig-ZMT.)
For Zomig nasal spray, the starting dose for migraine is 2.5 mg. There’s only one dose of 2.5 mg in each nasal spray bottle.
Zomig is typically taken at the first sign of a migraine attack. You may take a second dose of Zomig 2 hours after the first dose if your migraine doesn’t improve or starts to improve but comes back.
The maximum dose of Zomig taken at one time is 5 mg. Zomig’s maximum daily dose (amount you can take in a 24-hour period) is 10 mg.
Children’s dosage
Zomig nasal spray is the only form of Zomig approved for use in children ages 12 years and older. The typical starting dose is 2.5 mg. Your child may take a second dose of Zomig if their migraine does not improve or starts to improve but comes back after the first dose.
The maximum dose of Zomig that your child’s doctor will prescribe is 5 mg. The maximum daily dose for children is 10 mg.
Long-term treatment
Zomig is meant to be used as a long-term treatment. If you and your doctor determine that Zomig is safe and effective for you, you’ll likely take it long term.
Keep in mind that Zomig is not meant to be used every day. It isn’t known whether Zomig tablets are safe to use for treating more than three migraine episodes within a 30-day period. And it isn’t known whether Zomig nasal spray is safe to use for treating more than four migraine episodes within a 30-day period.
If you need to use Zomig more often than is recommended, talk with your doctor. They may suggest a different treatment for your migraine episodes.
The Zomig dosage your doctor prescribes will depend on several factors. These include:
- the severity of the condition you’re using Zomig to treat
- the form of Zomig you take
- your age
- other medications you may take
Other medical conditions you have can also affect your Zomig dosage.
Zomig comes in three forms. Below is information about how to take each form. Zomig can be taken with or without food.
Zomig oral tablets are tablets that you swallow. If your dosage is 1.25 mg, you’ll split a 2.5 mg tablet in half.
Zomig-ZMT is an orally disintegrating tablet that dissolves on your tongue. Be sure to keep Zomig-ZMT in its sealed packaging until you’re ready to take your dose. Zomig-ZMT tablets should not be broken in half.
For Zomig nasal spray, you’ll spray the medication into one nostril. Each bottle of Zomig nasal spray contains one dose of 2.5 mg. The “Instructions for use” section of the Zomig nasal spray prescribing information contains instructions on how to use this form.
Accessible drug labels and containersIf you’re having trouble reading your prescription label, talk with your doctor or pharmacist. Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.
If you’re having trouble opening medication bottles, ask your pharmacist about putting Zomig in an easy-open container. They also may recommend tools that can make it easier to open bottles.
It’s important that you don’t use more Zomig than your doctor prescribes. For some medications, taking more than the recommended amount may lead to side effects or overdose.
If you take more than the recommended amount of Zomig
Call your doctor right away if you believe you’ve taken too much Zomig. Another option is to call America’s Poison Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.
The dosages in this article are typical dosages provided by the drug manufacturer. If your doctor recommends Zomig for you, they will prescribe the dosage that’s right for you. Always follow the dosage that your doctor prescribes for you.
As with any drug, never change your dosage of Zomig without your doctor’s recommendation. If you have questions about the dosage of Zomig that’s right for you, talk with your doctor.
Besides learning about dosage, you may want other information about Zomig. These additional articles might be helpful to you:
- More about Zomig. For information about other aspects of Zomig, refer to this article.
- Side effects. To learn about side effects of Zomig, see this article. You can also look at the prescribing information for the Zomig nasal spray and the tablets.
- Details about migraine. For details about migraine, see our headache and migraine hub and these related articles.
Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
