Pancreatic lymphoma is a rare type of cancer originating from lymphocytes, a type of white blood cell, in the pancreas. It falls under the broader category of non-Hodgkin’s lymphoma, a group of lymphatic system cancers.
Pancreatic lymphoma can directly involve the pancreas or occur as a secondary manifestation of lymphoma that has spread from other parts of the body.
It is a
This article examines the different types of pancreatic lymphoma, including symptoms, diagnosis, treatment options, and outlook.
Different types of lymphoma can affect the pancreas, including those in the following two groups.
Primary pancreatic lymphoma
According to a
Diffuse large B-cell lymphoma is the
PPL may also present as the following:
- small lymphocytic lymphoma
- follicular lymphoma
- T-cell lymphoma, either of non-Hodgkin’s lymphoma or Hodgkin’s lymphoma.
Secondary pancreatic lymphoma
Secondary pancreatic lymphoma refers to lymphomas that
Secondary involvement of the pancreas can occur as part of more widespread lymphoma involvement. It is more common than PPL.
Difference between pancreatic cancer and lymphoma
However, other types of cancer can also affect the pancreas. Pancreatic adenocarcinoma is another type of the disease that originates from the cells lining the ducts of the pancreas.
According to a 2020 case report, symptoms of PPL can include the following:
Doctors may use a biopsy to diagnose non-Hodgkin’s lymphomas, such as pancreatic lymphoma. A pathologist will examine the biopsy tissue under a microscope to determine the type of lymphoma and its characteristics.
Doctors may also use the following tests to identify the extent of the pancreatic lymphoma:
- Blood tests: Blood samples can allow doctors to analyze the function of certain organs and check a person’s general health.
- Imaging tests: Imaging techniques, such as CT scans, MRI, and PET scans, visualize the pancreas and surrounding structures, helping doctors identify abnormalities and evaluate the extent of the disease.
According to a
Treatment options may include:
- Chemotherapy: Chemotherapy is the
main treatmentfor lymphoma. It uses drugs to kill or inhibit the growth of cancer cells. Doctors may use different chemotherapy plans according to the specific type of lymphoma.
- Radiation therapy: Radiation therapy uses high energy rays to target and destroy cancer cells. Doctors may use this in combination with chemotherapy.
- Immunotherapy: Immunotherapy stimulates the body’s immune system to recognize and attack cancer cells.
- Surgery: Surgery is
less commonfor pancreatic lymphoma in comparison with pancreatic adenocarcinoma. However, doctors may consider it in certain cases, especially for localized cancers.
The outlook for pancreatic lymphoma can vary depending on several factors, including the type of lymphoma, the stage at diagnosis, the patient’s overall health, and the response to treatment.
PPL is a rare condition, and the specific subtype of lymphoma may influence survival rates, making it challenging to provide precise figures.
However, a 2020 case report suggests that the 5-year survival rate for PPL is 26–66%.
Consulting with healthcare professionals who specialize in lymphomas and pancreatic conditions is the best way to get accurate and up-to-date information that is bespoke for a person’s specific situation.
Pancreatic lymphoma is a rare cancer originating from lymphocytes in the pancreas. It falls into the category of non-Hodgkin’s lymphoma and can develop directly in the pancreas or spread from elsewhere.
Symptoms of pancreatic lymphoma may include a swollen abdomen, abdominal pain, and nausea. People need to speak with a doctor if they suspect they have had issues with their pancreas.
Treatment typically involves chemotherapy. However, doctors may combine this treatment with others, such as radiotherapy.