Tyrosine is an amino acid that the body makes from a different amino acid called phenylalanine. As the body can naturally produce tyrosine, it is a nonessential amino acid.
People with the genetic disorder phenylketonuria (PKU) have a high risk of tyrosine deficiency because the body does not convert phenylalanine to tyrosine.
Tyrosine is a nonessential amino acid. The term nonessential means that a person does not need to get it through the diet, not that it is unimportant to health. The body can manufacture tyrosine naturally when a person gets sufficient quantities of the amino acid phenylalanine.
The disease PKU, which is present at birth, causes a dangerous buildup of phenylalanine.
Children and adults with this disorder should limit their intake of foods containing phenylalanine. This puts them at risk of tyrosine deficiency because the body does not convert phenylalanine to tyrosine.
Tyrosine helps the body make several important neurotransmitters, including those below. These chemicals help carry nerve signals across a synapse, playing a vital role in many important functions.
- Epinephrine: Also known as adrenaline, this chemical plays a critical role in the fight-or-flight response.
- Norepinephrine: The body releases this chemical along with epinephrine to increase heart rate and support the fight-or-flight response. It also provides energy by breaking down fat and increasing blood sugar.
- Dopamine: This neurotransmitter helps support feelings of pleasure, reward, and motivation. Its absence may
contribute tosexual dysfunction, depression, addiction, and attention.
When the body cannot produce these neurotransmitters in sufficient quantities, a person may experience concentration issues, mood changes, and difficulty managing stress.
Some research also suggests that tyrosine supplements may offer health benefits.
Not all research supports this idea, though. A
The authors of the study suggest that tyrosine supplements may induce an overdose in older people, causing harmful effects. They emphasize that most prior research on tyrosine has looked at young people and that these results may not be applicable to the wider population.
A 2017 study that included adults aged 24–40 years and older adults aged 61–88 years showed benefits in both groups. The researchers found that high tyrosine consumption correlated with better scores on a cognitive assessment regardless of age.
However, as the study looked at dietary tyrosine, it does not provide guidance about the potential risks and benefits of tyrosine supplements.
This suggests, but does not prove, that changes in how tyrosine behaves may play a role in the development of certain cancers.
High protein foods tend to be high in amino acids.
Some foods that are rich in phenylalanine, which the body needs to synthesize tyrosine, include:
- soy products, such as soybeans, tofu, and soy milk
- fish and meat, including chicken, turkey, and pork
- eggs and dairy products, such as milk and cheese
- seeds, including pumpkin and sesame seeds
- beans, such as lima beans
Vegetarians and vegans may need to focus on eating more high protein foods, such as tofu, to ensure that they get enough tyrosine and other amino acids.
A doctor or dietitian can offer advice on how people with PKU can get enough tyrosine without eating phenylalanine.
A person can also take a tyrosine supplement, but the right dosage varies among individuals. It is important to talk with a doctor before taking any new supplements.
Tyrosine is vital for good health, and its absence can mean that the body does not make enough neurotransmitters to support attention, cognition, and mood.
Whole foods rich in phenylalanine can help a person meet their daily tyrosine needs, but meeting these needs can be difficult for people with PKU. A doctor can help these individuals understand how to get enough tyrosine.
People without PKU considering tyrosine supplements should weigh the risks and benefits, especially if they are over the age of 60 years, since some research suggests high levels of tyrosine may be harmful after this age.