Systolic congestive heart failure occurs when the heart does not pump blood effectively. It may happen when the heart muscle is too weak or when another health problem prevents it from circulating blood efficiently.
Over time, systolic congestive heart failure, or heart failure (HF), can lead to dysfunction of other organs due to inefficient pumping.
In this article, we describe how HF progresses over time and explain the outlook for people with this condition. We also examine the causes, symptoms, and treatment options.
There are four different stages of HF: A, B, C, and D.
When the condition progresses to the next stage, a person’s chance of surviving for 5 or more years decreases.
People with stage A HF do not yet have dysfunction of the pumping activity of the heart but have a high risk of developing HF due to related conditions, such as chronic high blood pressure, diabetes, and coronary artery disease.
People with this stage HF have no problems with the structure of the heart or how their heart works. They will also rarely experience any symptoms of HF but may have symptoms related to their other conditions.
Structural heart disease develops at this stage, such as reduced pumping function of the heart, which can lead to an enlarged left ventricle. It can also result from a previous heart attack. However, people with HF stage B remain asymptomatic.
People at this stage will show symptoms of HF linked to underlying structural heart disease, including fatigue or breathlessness. These symptoms usually occur due to problems with the squeezing function of the left ventricle, or the pumping chamber of the heart.
Stage C HF also includes people who no longer show symptoms but are currently undergoing treatment for previous symptoms (such as those who spent time in the hospital with heart failure exacerbation).
At stage D, people will have advanced structural heart disease and display significant symptoms, even when they are at rest.
This stage is severe and may require advanced specialized treatment, such as mechanical circulatory support, continuous inotropic infusion to make the heart squeeze harder, cardiac transplant, or hospice care.
The most common type of HF is left-sided HF. The left side of the heart must work harder to move the same volume of blood around the body. This may cause a fluid buildup in the lungs and make breathing difficult as it progresses.
These fluids give congestive heart failure its name.
There are two kinds of left-sided HF:
- Systolic heart failure: The left ventricle cannot contract normally, limiting the heart’s pumping ability.
- Diastolic heart failure: The muscle in the left ventricle stiffens. If the muscle cannot relax, the pressure in the ventricle increases, causing symptoms.
Right-sided HF is less common. It occurs when the right ventricle cannot pump blood to the lungs. This can lead to blood backing up in the blood vessels, which may cause fluid retention in the lower legs and arms, abdomen, and other organs.
A person can have left-sided and right-sided HF at the same time. However, HF usually begins on the left side and can affect the right side if a person does not receive effective treatment.
Symptoms of HF range from mild to severe but may get worse over time if not managed medically.
Lifestyle strategies can reduce the risk of developing HF and can also slow its progress.
To prevent or slow the progression of HF, people should take the following steps:
- Maintain a healthy body weight: Excess body weight can place strain on the heart and increase the risk of more damage to the heart.
- Exercise regularly: The AHA recommends getting 150 minutes of moderate-intensity exercise every week. Those individuals with heart failure should talk to their doctors about getting an individualized exercise “prescription.”
- Manage stress: Meditation, therapy, and relaxation techniques can help a person manage stress, which can have adverse effects on the heart.
- Eat a heart-healthy diet: Daily food intake should be low in trans fats, rich in whole grains, and low in sodium and cholesterol. Experts often recommend that people with heart failure limit their sodium intake to 2,000 milligrams (mg) daily and consume 2 liters (l) of fluid. However, individuals should check with their doctor what their sodium and fluid intake should be.
- Monitor blood pressure regularly: A doctor can do this at regular check-ups. However, doctors also recommend people use home blood pressure monitors, or sphygmomanometers.
- Vaccinations: Be sure to stay on top of vaccinations for influenza and pneumococcal pneumonia.
- Treat and manage risk factors such as hypertension, smoking, alcohol, drugs, diabetes
People who already have HF should take the following steps to prevent further progression:
- avoid alcohol
- limit caffeine and other stimulants
- get adequate rest
- track changes in their symptoms and exercise capacity
- monitor daily weights
- check blood pressure and heart rate at home
Without treatment, HF can be fatal. Even with adequate treatment, HF may get worse over time, triggering dysfunction of other organs throughout the body.
HF is more likely to occur in people with other conditions or lifestyle factors that weaken the heart.
Risk factors for HF include:
- congenital heart anomalies
- high blood pressure or cholesterol
- chronic obstructive pulmonary disease (COPD) and coronary heart disease
- cardiovascular conditions, such as valvular heart disease
- heart infection
- reduced kidney function
- a history of heart attacks
- irregular heart rhythms or arrhythmias
- abuse of alcohol or illicit drugs
- older age
People with a history of cardiovascular health issues or several risk factors for HF should seek immediate care if they experience symptoms of HF.
The most common symptoms of HF are:
- Shortness of breath or difficulty breathing: People with HF may also struggle to breathe when lying down, with activity or at rest due to fluid accumulation in the lungs.
- A persistent, unexplained cough: Some people experience wheezing and pink, or blood-stained mucus.
- Swelling in the legs, ankles, abdomen, or hands: The swelling may get worse as the day goes on or after exercise.
- Weight gain: Rapid weight gain may be a sign of congestive heart failure.
- Feeling tired: Even well-rested people can experience fatigue.
- Changes in thinking and memory: Electrolyte imbalances due to HF can impair a person’s ability to think clearly.
- Nausea: A reduced appetite can accompany this.
- A rapid heart rate: This occurs because the heart is unable to pump blood with a regular rhythm.
- Light-headedness, dizziness, or passing out: This might also include tingling or numbness in the extremities due to an inadequate blood supply.
As fluid builds up, people with HF may develop painful swelling, or edema.
Swelling caused by HF can undermine movement and may lead to skin changes and skin breakdown. Fluid retention may also affect other organ function, making it harder to breathe or exercise.
Children with HF may experience delays in physical development, while infants with the condition may struggle to gain weight.
A doctor or cardiologist will perform a physical exam. This involves listening to the heart, checking for fluid retention, and looking at the veins in the neck to see if there is extra fluid present in the heart. They may order other diagnostic tests, including:
- Electrocardiogram: This records the heart’s electrical rhythm.
- Echocardiogram: This is an ultrasound test that can help a doctor determine if a person has a leaky heart valve, a heart muscle that is not squeezing or relaxing properly.
- Stress tests: These tests show how the heart performs under different levels of cardiac stress, such as during exercise. Sometimes, they involve using medications that stimulate the heart to beat faster and harder or cause the blood vessels to relax.
- Blood tests: A doctor may request these to check for infections, assess kidney function, and levels of brain natriuretic peptide (BNP). BNP is a “stretch” hormone that indicates stretching or increased pressure that occurs with HF.
- MRI: This can provide high-resolution images of the heart and can assess for structural changes and scarring.
- Cardiac catheterization: This can help a doctor identify blockages in the arteries, one of the most common causes of HF. A doctor may check blood flow and pressure levels in the ventricles at the same time.
Different medications can help symptoms of and prognosis in HF. These include:
- Blood thinners: These reduce the risk of blood clots, which might break loose and travel to the body, heart, lungs, or brain. Blood thinners carry risks, such as increased bleeding.
- Angiotensin receptor-neprilysin inhibitors: These help reduce the risk of mortality and decrease congestion in the heart.
- ACE inhibitors: These relax the blood vessels and help reduce the impact of heart failure.
- Angiotensin receptor blockers: These work to reduce tension in the blood vessels.
- Anti-platelet drugs: Doctors prescribe these to stop blood clots because they prevent platelets in the blood from sticking together.
- Beta-blockers: These drugs lower the heart rate, the force of the heartbeat, and blood pressure, helping to “rest” the heart.
- Sino-atrial node modulators: These can help further reduce the heart rate in people who are already taking beta-blockers.
- Statins: People use these to reduce levels of low-density lipoprotein (LDL), or “bad” cholesterol and increase high-density lipoprotein (HDL), or “good” cholesterol levels.
- Diuretics: These help the body excrete excess fluid in the urine and remove it from the heart and lungs. They also reduce swelling and prevent shortness of breath.
- Vasodilators: These reduce the amount of oxygen that the heart needs to dilate. They can also ease chest pain.
People with advanced HF might need more intensive treatment. Medical procedures that may help include the following:
People with advanced HF might need more intensive treatment. A surgeon might implant a medical device, such as:
- An implantable defibrillator: These can prevent arrhythmias.
- A pacemaker: These address electrical problems in the heart to help the ventricles contract more regularly.
- Cardiac resynchronization therapy: This helps to regulate heart rhythm and reduce arrhythmia symptoms.
- A left ventricular assist device (LVAD): This supports the pumping ability of a heart when it cannot do this efficiently on its own. People once used LVADs on a short-term basis but can now use them as part of long-term treatment.
A doctor may recommend some other procedures for treating HF, including:
- Percutaneous coronary intervention to open a blocked artery: The doctor may place a stent to help keep the vessel open.
- Coronary artery bypass surgery: This reroutes some of the blood vessels so the blood can travel to supply oxygen to the heart while avoiding diseased or blocked blood vessels.
- Valve replacement or repair surgery: A doctor can replace or repair an inefficient or diseased valve with a mechanical valve or one developed from living tissue.
- Heart transplant: This may be the only remaining option if other treatments are not effective.
Not everyone with HF is an appropriate candidate for a transplant, and people often have to wait a long time before having one.
Heart surgery can be dangerous and invasive but is sometimes necessary, in combination with medications, to help treat HF in the best possible way.
Will HF always cause symptoms before it becomes dangerous?
Not always; it depends on the cause of HF. Sometimes advanced HF is indolent and presents with symptoms only in its very advanced stages.
For this reason, it is essential to control risk factors that may cause stage A HF and follow up regularly with your doctor.