Pinpoint pupils occur when the pupils shrink to a small size. This can be due to various conditions and medications, such as prescription opioids, hypertension medications, and eye inflammation.

In typical conditions, the pupils change size to let in the right amount of light. In the dark, they open wider or dilate to let in more light. In bright light, they get smaller or constrict to prevent too much light from entering.

However, some medical conditions and certain drugs can cause the pupils to shrink to a pinpoint size.

The medical term for pinpoint pupils is miosis or myosis, from an ancient Greek word “muein,” meaning “to close the eyes.”

This article looks at the potential causes and treatment options for pinpoint pupils.

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Some medications have opioids or narcotics in them. Opioids, including morphine, are drugs commonly prescription medication for pain relief. Opioids can affect a person psychologically and are highly addictive.

Pinpoint pupils can be a sign of opioid overdose, alongside:

Treatment

Opioid overdoses can be fatal without treatment. Anyone with a suspected overdose needs emergency medical attention.

A doctor will prescribe a medication called naloxone to the person experiencing an overdose. This medication blocks the effects of opioids.

A doctor might also refer them to a treatment and recovery program if they have a drug dependency.

Some medications prescribed for high blood pressure, which is known as hypertension, can also cause pinpoint pupils. One example is clonidine.

Treatment

Anyone who thinks their hypertension medication may be causing pinpoint pupils needs to consult their doctor. The doctor may be able to prescribe a different form of medication.

Suicide prevention

If you know someone at immediate risk of self-harm, suicide, or hurting another person:

  • Ask the tough question: “Are you considering suicide?”
  • Listen to the person without judgment.
  • Call 911 or the local emergency number, or text TALK to 741741 to communicate with a trained crisis counselor.
  • Stay with the person until professional help arrives.
  • Try to remove any weapons, medications, or other potentially harmful objects if it’s safe to do so.

If you or someone you know is having thoughts of suicide, a prevention hotline can help. The 988 Suicide and Crisis Lifeline is available 24 hours a day at 988. During a crisis, people who are hard of hearing can use their preferred relay service or dial 711 then 988.

Find more links and local resources.

Heroin is a highly addictive recreational opioid. While taking the drug, the pupils can become smaller in size. Other symptoms of heroin use and addiction include:

  • bloodshot or red eyes
  • weight loss
  • extreme sleepiness and falling asleep at inappropriate moments
  • secretive behavior
  • lack of motivation
  • thoughts of self-harm or suicide
  • slurred speech
  • paranoia
  • extreme itchiness

People using heroin are at risk of contracting blood infections by sharing needles. Injecting heroin can also damage the veins and arteries and may cause gangrene.

Heroin can also cause respiratory failure, which is when a person stops breathing, or death by inhaling vomit, as it limits someone’s ability to cough properly.

Treatment

A person with a heroin dependency needs to consult a doctor or a local drug treatment center.

A healthcare professional will ask about their drug use, family and housing situation, and any other contributing factors the person may wish to disclose. The doctor may request a urine or saliva sample.

Treatment options are available, depending on the person’s needs. These include:

  • talk therapy, cognitive behavioral therapy (CBT), or other counseling
  • medications such as methadone and naloxone
  • support groups
  • detoxification

Horner’s syndrome is a rare condition due to a tumor, a stroke, or damage to the central trunk of the brain, or the brainstem. It affects a type of nerve called the sympathetic nerve.

Symptoms include:

  • pinpoint pupil on one side of the face
  • drooping of the upper eyelid over the affected eye, known as ptosis
  • an inability to sweat on one side of the face, in some cases

Treatment

Treatment for Horner’s syndrome can depend on its cause. In some cases, treatment may be necessary.

Anterior uveitis is inflammation of the eye’s middle layer, including the iris. It can cause the pupil to become smaller and atypical in shape.

Although it can affect anyone, it mostly occurs in people ages 20 to 60.

It can appear in one or both eyes. Other symptoms include:

Treatment

Treatments for pinpoint pupils due to anterior uveitis include using eye drops to open up the pupil or using eye drops that contain steroids to reduce inflammation.

A doctor or eye specialist, known as an ophthalmologist, may refer a person for further testing if they suspect an underlying medical condition to be the cause.

Pinpoint pupils after a head injury can indicate a herniation, meaning that the brain tissue has shifted from one space in the skull to another. Brain herniation occurs due to increased pressure in the skull, which can be due to brain swelling or bleeding from a head injury.

Head injuries can cause severe and even life threatening complications, even if the effects are not immediately apparent. Anyone who has experienced a head injury needs to seek immediate medical attention.

Exposure to pesticides known as organophosphates can cause pinpoint pupils in severe cases. The person may also show signs of:

Treatment

Anyone who thinks they or someone else has been poisoned by a pesticide, household cleaner, or other toxic product requires immediate medical attention.

If a person is unconscious or vomiting, it is important to roll them onto their side if possible and keep their head tilted slightly downward. This position will ensure any vomit can escape without the person choking on it.

Medical treatments for poisoning include:

  • activated charcoal
  • antidotes, if possible
  • anti-seizure medications
  • sedatives
  • a breathing machine known as a ventilator

Pinpoint pupils are not a disease alone but can indicate an underlying medical problem. Anyone experiencing pinpoint pupils with no apparent cause needs to speak with a doctor immediately.

Many of the causes of pinpoint pupils are serious medical conditions, such as opioid dependency or pesticide poisoning. Early intervention can help prevent life threatening complications.

Even anterior uveitis can cause permanent eye damage and blindness without treatment. However, it is usually a less serious form of uveitis.

The outlook for conditions that cause pinpoint pupils improves when people seek treatment quickly and follow a doctor’s advice for a complete recovery.

The following are commonly asked questions about pinpoint pupils.

What do pinpoint pupils indicate?

Pinpoint pupils can indicate an underlying medical condition, such as a severe head injury or anterior uveitis. It can also develop as a result of prescription medications, including prescription opioids and some high blood pressure medications.

What emotion causes pinpoint pupils?

Sadness can result in smaller pupils. Research from 2018 found that crying can trigger the pupillary system, resulting in smaller pupils.

Pinpoint pupils can be a side effect of certain medications, such as high blood pressure medications or prescription opioids.

They can also signal an underlying medical condition, such as stroke, head injury, or eye condition.

A person needs to seek medical help immediately if they develop pinpoint pupils, as some causes can have severe complications.