Research suggests that having psoriasis can increase people’s risk of developing certain cancers. However, more research is necessary to fully establish the link.
Psoriasis is a chronic autoimmune disease that causes the skin to reproduce more rapidly than usual. The abnormal growth typically causes skin discoloration and scaly patches to form on the skin.
This article further explores psoriasis and its potential link to cancer.
People with psoriasis may also have an increased risk of lymphoma, throat, pancreatic, and liver cancer, according to
Mechanisms of the link
It is unclear whether it is psoriasis itself or common psoriasis treatments, such as immune-suppressing medications and UV treatments, that may increase a person’s risk of cancer.
A 2020 review states that some common psoriasis treatments may carry an increased risk of nonmelanoma skin cancer. These include psoralen and ultraviolet A (PUVA) therapy, the immunosuppressant drug cyclosporine, and tumor necrosis factor (TNF) inhibitors.
Psoriasis may be a risk factor for developing cancer, but doctors do not consider it a direct cause of cancer. Also, cancer cannot cause psoriasis.
The exact link between psoriasis and cancer is
Psoriasis and skin cancers are two distinct conditions, both with multiple types. However, some forms of skin cancer may produce visible symptoms similar to certain types of psoriasis.
It is important for a person to talk with their doctor if they notice any sudden changes in their skin.
Psoriasis tends to be pink or red on those with light or fair skin tones, and the scales are silvery white. On medium skin tones, it can appear salmon-colored with silvery-white scales. On darker skin tones, psoriasis could look violet and the scales gray. Or it can also appear dark brown and difficult to see.
Other psoriasis symptoms can include:
- cracked or dry skin that may bleed
- burning, itching, or pain
- thickened fingernails
- a firm, taut texture
- often shiny, raised, pearly, or waxy
- oddly colored
- scaling, bleeding, or crusting
- blurred or rough edges
- changing and growing over time without disappearing
- distinguished by rapid growth
- asymmetrical in shape
- often brown but also dark blue, red, white, yellow, or black
Psoriasis often covers large portions of the body. Skin cancer tends to be smaller and occurs when the skin is regularly exposed to the sun, though it can affect any skin area.
Psoriasis often goes through phases of outbreaks followed by recession. Skin cancer will change over time, and the symptoms may become more severe without treatment.
Psoriasis does not cause cancer, and cancer does not cause psoriasis. But a person with psoriasis may have a
The exact physical link between psoriasis and cancer development is unknown. Research suggests that increased inflammation due to psoriasis and side effects of psoriasis treatments may be behind the increased likelihood of some cancers appearing.