Cutaneous lupus is a type of autoimmune disease that causes skin inflammation. Lupus causes inflammation throughout the body, with a wide range of symptoms, but the cutaneous form affects only the skin.
Lupus is a long-term condition in which the body’s immune system mistakenly attacks healthy tissues. It can affect most organs in the body, causing a wide range of symptoms. The
Lupus has many types, and the symptoms vary depending on which organs the disease affects. Lupus that affects the skin is known as cutaneous lupus. People with cutaneous lupus typically experience only symptoms that affect the skin, but they can develop other conditions that cause further symptoms.
In this article, we will discuss cutaneous lupus, including its forms, causes, and treatment options.
Cutaneous lupus is an autoimmune condition that affects the skin. Autoimmune conditions occur when the body’s immune system mistakenly attacks healthy tissues, causing inflammation. Inflammation is a normal bodily response to germs or injuries, but it can become harmful when the body does not regulate this response as usual.
The Lupus Foundation of America estimates that around two-thirds of people with lupus will develop cutaneous lupus at some point.
There are several types of cutaneous lupus that cause lesions in different forms and locations around the body. These lesions may be painful and itchy, or they may cause no further symptoms at all. In all forms of cutaneous lupus, sun exposure makes symptoms worse.
There are four main types of cutaneous lupus:
- Acute: This form of the condition can occur with systemic lupus erythematosus and causes a butterfly-shaped lesion across the nose and cheeks. The symptoms typically occur after sun exposure. The condition causes itchy, flat, red or otherwise discolored areas of skin.
- Subacute: This subtype can occur on its own or with systemic lupus. It causes lesions that are not typically painful or itchy. Some lesions may appear similar to pimples, and others may look like flat circles that are pink with a red ring or otherwise discolored.
- Intermittent: Also known as lupus tumidus, this type
causeslesions that appear on sun-exposed areas of the body and typically resolves in winter.
- Chronic: This condition causes lesions around the head, neck, and hands that are typically not painful or itchy. There are several types of chronic cutaneous lupus. Discoid lupus, which causes coin-shaped lesions, is the most common subtype.
Cutaneous lupus results from the immune system mistakenly attacking healthy tissues. However, the cause of this dysfunction is not clear.
- genetic factors
- environmental factors such as sunlight and viruses
- immune and inflammatory influences, such as an inability of the body to remove damaged cells
Certain medications, including some chemotherapy drugs and proton pump inhibitors, can also result in cutaneous lupus. The Arthritis Foundation estimates that around 20% of cutaneous lupus cases could be due to medications.
The symptoms of cutaneous lupus result from inflammation. People with lupus usually experience rashes, sores, or other lesions on the skin. These symptoms typically occur in response to sunlight and appear in areas of skin exposed to the sun, such as the:
Different types of cutaneous lupus will cause
Subacute cutaneous lupus may cause scaly, red or otherwise discolored patches that appear similar to pimples. Alternatively, it can cause sores that appear similar to psoriasis, which may be pink with a red ring or otherwise discolored. Some people with the condition may have both types of lesions.
Intermittent cutaneous lupus is an uncommon variant that features a red-pink, raised, itchy rash that occurs on sun-exposed areas of skin. The lesions resolve in winter without scarring.
People with chronic cutaneous lupus can experience different symptoms depending on the subtype they have. The lesions can cause permanent scarring or changes in skin color.
Doctors will diagnose cutaneous lupus after performing a physical examination and checking the person’s medical history. They will check the skin for lesions and note their type, spread, and location. They might also order blood and urine tests or take a skin sample.
There is currently no cure for cutaneous lupus, but treatments are available to manage symptoms. The Arthritis Foundation states that the two primary types of treatment are as follows:
To reduce symptoms and improve the appearance of the skin, doctors may suggest lifestyle strategies such as:
- avoiding drugs that trigger symptoms
- stopping smoking
- reducing sun exposure and protecting the skin during sun exposure, such as by wearing sunscreen
Several drug treatments are available for cutaneous lupus depending on its severity and spread. These include:
- steroid creams to reduce inflammation
- calcineurin inhibitors to reduce the side effects of steroids
- antimalarial drugs
- methotrexate or anti-inflammatory drugs such as dapsone
It is advisable for anyone with symptoms of cutaneous lupus to contact a doctor. Without treatment, cutaneous lupus could become severe.
It could be easy to miss the symptoms of cutaneous lupus or mistake them for symptoms of another condition. For example, acute cutaneous lupus causes a rash across the face that may appear similar to rosacea or psoriasis. Anyone who experiences lupus symptoms should be careful not to overlook them and should contact a doctor.
Cutaneous lupus is an autoimmune condition that affects the skin. It results from inflammation, which can lead to rashes and lesions around the body. There are four main types of cutaneous lupus that cause different types of lesions.
There is currently no cure for cutaneous lupus. However, treatments are available to manage the symptoms. People with any form of cutaneous lupus should avoid sun exposure and protect their skin when in sunlight. The sun can trigger symptoms of cutaneous lupus.