Calquence (acalabrutinib) is a brand-name drug that’s prescribed for certain types of lymphoma and leukemia in adults. The medication is available in these forms: oral capsule and oral tablet. The cost of Calquence with and without insurance can depend on several factors, such as whether the drug has a savings program.
Specifically, the Food and Drug Administration (FDA) has approved Calquence for the following in adults:
As with all medications, the cost of Calquence can vary. Factors that may affect the price you’ll pay include:
- your treatment plan
- your insurance coverage
- the pharmacy you use
- whether Calquence has a savings program (see the “Financial and insurance assistance” section below)
To find out what the cost of Calquence will be for you, talk with your doctor, pharmacist, or insurance provider. Or look below in the next section to learn how much you can save by using an Optum Perks coupon.
To save money on your Calquence prescription, explore these Optum Perks coupons.
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Retail price refers to the manufacturer’s published list price and is up to date as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.
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Calquence is only available as a brand-name drug. It doesn’t come in a generic version. A generic drug is an exact copy of the active drug in a brand-name medication.
Generics tend to cost less than brand-name drugs.
WHY ARE COSTS DIFFERENT FOR BRAND-NAME DRUGS VS. GENERIC DRUGS?
Brand-name drugs can be expensive because of the research needed to test their safety and effectiveness. The manufacturer of a brand-name drug can sell it for up to 20 years. When the brand-name drug’s patent expires, multiple manufacturers can create generic versions. This marketplace competition may lead to lower costs for generics. Also, because generics contain the same active ingredients as brand-name drugs, they don’t require the same costly testing.
If you take Calquence long term, you may be able to lower its cost in the following ways.
Getting a 3-month supply
You may be able to get a 90-day supply of Calquence. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. If you’re interested in this option, check with your doctor, pharmacist, or insurance provider.
Using a mail-order pharmacy
Calquence may be available through a mail-order pharmacy. Using this type of service may help lower the drug’s cost and allow you to receive your medication without leaving home. Some Medicare plans may help cover the cost of mail-order medications. You may also be able to get a 90-day supply of the drug via mail order.
If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.
If you need financial support to pay for Calquence, or if you need help understanding your insurance coverage, help is available. For example:
- A program called the Calquence Patient Savings Program is available for Calquence. For more information and to find out if you’re eligible for support, call 844-275-2360 or visit the program website.
- If you have Medicare or do not have insurance coverage, a program called the AstraZeneca Prescription Savings Program is available. For more information, call 800-292-6363 or visit the program website.
- Some websites provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services. Two such websites are:
To learn more about saving money on prescriptions with or without insurance, check out this article.
Here are answers to some frequently asked questions about drug cost and Calquence.
Is Calquence covered by Medicare?
It may be. You can call your Medicare plan provider to learn whether your particular plan covers the cost of this drug. There are many types of Medicare plans, so your coverage and what you pay for prescriptions will be based on your particular plan’s benefits.
You may also need to obtain prior authorization before your plan will cover the cost of this medication.
Your doctor may also be able to provide information about your cost for Calquence if you have Medicare.
How does Calquence’s cost compare with that of medications such as Imbruvica?
The price you would pay for Calquence versus that of Imbruvica depends on various factors.
For instance, the form of the drug may affect its price. Calquence is available as oral capsules and tablets, and Imbruvica is available as oral capsules, tablets, or suspension.
There are additional factors that can affect your prescription cost, including:
- the length of your treatment
- whether there are payment assistance programs for your prescribed treatment
- whether you’re paying out of pocket or have insurance
To learn more about the cost of Calquence compared with other treatments for your condition, talk with your doctor, pharmacist, or insurance provider.
What is the cost of Calquence without insurance?
The price you’ll pay for Calquence if you don’t have insurance can vary based on several factors. But typically, the cost is higher for those without insurance.
There are other factors that could affect what you pay for this drug. These include:
- the quantity you’re prescribed (such as a 90-day or 30-day supply)
- whether you apply and qualify for any available savings programs
- your dosage
- the pharmacy you use
- the form of the drug you’re prescribed (such as oral capsules or tablets)
To learn the exact cost you’d pay for this medication without insurance, ask your doctor or pharmacist. You may also want to contact several pharmacies to compare their prices for Calquence.
Check out Optum Perks* for estimates of Calquence’s price when using coupons from the site. (Optum Perks coupons cannot be used with insurance benefits or copays.)
* Optum Perks is a sister site of Medical News Today.
Below is information you may want to consider if you have insurance and receive Calquence.
If you have insurance, your insurance company may require prior authorization before it covers Calquence. This means the company and your doctor will discuss Calquence in regard to your treatment. The insurance company will then determine whether the medication is covered.
If a drug requires prior authorization but you start treatment without the prior approval, you could pay the full cost of the medication. You can ask your insurance company whether Calquence requires prior authorization.
Now that you’ve learned about cost and Calquence, you may still have some questions. Talk with your doctor or pharmacist, who can provide personalized guidance about cost issues related to Calquence. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you would pay for Calquence.
Here are some other resources you may find helpful:
- Medicare drug coverage: To learn about Medicare coverage for drugs, see these articles about Medicare prescription drug plans, drug coupons and Medicare, and the Medicare drug list.
- More details: For details about other aspects of Calquence, refer to this article.
- Dosage: Learn about Calquence and dosage by viewing this article.
- Side effects: For details about Calquence’s side effects, see this article. You can also look at the Calquence prescribing information.
- Interactions: You can find out more about what Calquence interacts with by visiting this article.
- Information about your: For more information about your condition, see our leukemia hub and and cancer hub.
Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.