Metolazone is a generic oral tablet that’s prescribed for high blood pressure and other conditions in adults. It’s not available in a brand-name version. The cost of metolazone with and without insurance can depend on several factors.

Metolazone is approved by the Food and Drug Administration (FDA) to treat edema due to:

It’s also approved to treat high blood pressure when prescribed alone or with other blood pressure medications.

As with all medications, the cost of metolazone can vary. Factors that may affect the price you’ll pay include your treatment plan, your insurance coverage, and the pharmacy you use.

To find out what the cost of metolazone will be for you, talk with your doctor, pharmacist, or insurance provider. Or look below in the next section to learn how much you can save by using an Optum Perks coupon.

To save money on your metolazone prescription, explore these Optum Perks coupons.

Save on metolazone with Optum Perks

Save on metolazone without insurance.

Enter your information:




2.5mg metolazone (30 Tablets)

Save on metolazone

Simply show the Optum Perks coupon at your preferred pharmacy and instantly save without using insurance. The coupon doesn't expire, so be sure to save it for use with refills.

Find your pharmacy

Retail price refers to the manufacturer’s published list price and is up to date as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.

Optum Perks and Healthline are subsidiaries of RVO Health.



Was this helpful?

Metolazone is only available as a generic drug. It doesn’t come in a brand-name version. A generic drug is an exact copy of the active drug in a brand-name medication. Metolazone was based on the discontinued brand-name drugs Zaroxolyn, Mykrox, and Diulo.

Generics tend to cost less than brand-name drugs.

If you take metolazone long term, you may be able to lower its cost in the following ways.

Getting a 3-month supply

You may be able to get a 90-day supply of metolazone. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. If you’re interested in this option, check with your doctor, pharmacist, or insurance provider.

Using a mail-order pharmacy

Metolazone may be available through a mail-order pharmacy. Using this type of service may help lower the drug’s cost and allow you to receive your medication without leaving home. Some Medicare plans may help cover the cost of mail-order medications. You may also be able to get a 90-day supply of the drug via mail order.

If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need financial support to pay for metolazone, consider looking into websites that offer cost resources and information. Two such organizations are:

These sites can provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services.

Here are answers to some frequently asked questions about drug cost and metolazone.

How much does metolazone cost with insurance vs. without it?

What you pay for metolazone with or without insurance depends on several factors.

Factors that could affect what you pay for this drug without insurance include:

  • the quantity you’re prescribed (such as a 90-day or 30-day supply)
  • whether you apply and qualify for any available savings programs
  • your dosage and treatment plan
  • the pharmacy you use

These same factors may affect your price for metolazone if you have insurance. However, the price you pay with insurance will also depend on:

  • your specific plan benefits
  • any prior authorization requirements you have for drug coverage

To learn more about what you’d pay for metolazone with or without insurance, talk with your doctor, pharmacist, or insurance provider (if you have one).

You can also visit Optum Perks* for price estimates for this drug when using coupons from their site. However, Optum Perks coupons cannot be used with insurance benefits or copays.

* Optum Perks is a sister site of Medical News Today.

How does metolazone’s cost compare with that of medications such as furosemide?

Metolazone and furosemide (Lasix) are both drugs that may be prescribed to manage edema and high blood pressure. The price you would pay for either drug depends on various factors.

For instance, the form of the drug may affect its price. Metolazone and furosemide are both available as oral tablets. However, furosemide is also available as an oral solution and an intravenous (IV) injection. Typically, an IV injection costs more than an oral tablet.

There are additional factors that can affect your prescription cost, including:

  • the length of your treatment
  • whether there are payment assistance programs for your prescribed treatment
  • whether you’re paying out of pocket or have insurance

To learn more about the cost of metolazone compared with other treatments for your condition, talk with your doctor, pharmacist, or insurance provider.

Below is information you may want to consider if you have insurance and receive metolazone.

If you have insurance, your insurance company may require prior authorization before it covers metolazone. This means the company and your doctor will discuss metolazone in regard to your treatment. The insurance company will then determine whether the medication is covered. If a drug requires prior authorization but you start treatment without the prior approval, you could pay the full cost of the medication. You can ask your insurance company whether metolazone requires prior authorization.

Now that you’ve learned about cost and metolazone, you may still have some questions. Talk with your doctor or pharmacist, who can provide personalized guidance about cost issues related to metolazone. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you would pay for metolazone.

Here are some other resources you may find helpful:

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.