Rezurock (belumosudil) is a brand-name drug that’s prescribed for chronic graft-versus-host disease in adults and some children. Rezurock comes as an oral tablet that’s typically taken once per day.
Rezurock belongs to a drug class called kinase inhibitors. Rezurock isn’t available in a generic version.
Keep reading for specific information about the dosage of Rezurock, including its strength and how to take the medication. For a comprehensive look at Rezurock, see this article.
Note: This article describes typical dosages for Rezurock provided by the drug’s manufacturer. When taking Rezurock, always follow the dosage prescribed by your doctor.
Read on for details about Rezurock’s dosage for its approved use.
Rezurock comes as an oral tablet.
Rezurock comes in one strength: 200 milligrams (mg).
The following information describes dosages that are commonly prescribed or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.
Dosage for chronic graft-versus-host disease
Rezurock is prescribed for chronic graft-versus-host disease (GVHD) in adults. It’s used in cases that haven’t improved after at least two other therapies. The recommended dosage is 200 mg once per day.
Rezurock is prescribed for chronic GVHD in children ages 12 years and older. The recommended dosage for children is the same as the adult dosage: 200 mg once per day.
Rezurock is meant to be a long-term treatment. If you and your doctor determine that Rezurock is safe and effective for you, you’ll likely take the drug long term. You’ll take the dosage your doctor prescribes as long as your condition does not worsen.
The Rezurock dosage your doctor prescribes will depend on several factors. These include:
- other medications you may take
- certain side effects that you may have while taking Rezurock
- other medical conditions you have
Your doctor may need to increase your dosage if you take certain medications. These include CYP3A4 inducers and proton pump inhibitors (PPIs).* To learn more about Rezurock interactions, see this article. Let your doctor know about all the medications you take.
Rezurock comes as a tablet you swallow whole with a glass of water. Do not break, crush, or chew the tablets. Rezurock should be taken with a meal.
It may be helpful to take Rezurock at around the same time of day. This helps maintain a steady level of the drug in your body so Rezurock can work effectively.
If you have trouble swallowing tablets, see this article for tips on how to take this form of medication. You can also talk with your doctor or pharmacist.
ACCESSIBLE DRUG LABELS AND CONTAINERS
Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.
If you’re having trouble opening medication bottles, ask your pharmacist about putting Rezurock in an easy-open container. They also may recommend tools that can make it easier to open bottles.
If you miss a dose of Rezurock, take it as soon as you remember. Then, take your next dose of Rezurock at your regular time on the next day. Do not take two doses at once to make up for the missed one.
To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or putting a note where you’ll see it, such as on your bathroom mirror or bedside table. You could also download a reminder app on your phone.
It’s important that you do not take more Rezurock than your doctor prescribes. For some medications, taking more than the recommended amount may lead to side effects or overdose.
If you take more than the recommended amount of Rezurock
Call your doctor right away if you believe you’ve taken too much Rezurock. Another option is to call America’s Poison Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.
The dosages in this article are typical dosages provided by the drug’s manufacturer. If your doctor recommends Rezurock for you, they’ll prescribe the dosage that’s right for you. Always follow the dosage that your doctor prescribes.
As with any drug, never change your dosage of Rezurock without your doctor’s recommendation. If you have questions about the dosage of Rezurock that’s best for you, talk with your doctor.
Besides learning about dosage, you may want other information about Rezurock. These additional articles might be helpful:
- More about Rezurock. For information about other aspects of Rezurock, refer to this article.
- Details about your condition. For details about your condition, see our list of articles about blood and hematology and the immune system and vaccines.
Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.