Osteoporosis is a disease that affects bone and causes a reduction in bone mineral density and bone mass. Infusion therapy is a treatment option that involves injecting medication into a person’s bloodstream to help treat symptoms.
Osteoporosis is a condition that affects bone health. It occurs when the body reabsorbs more bone tissue and produces less to replace it, resulting in bones becoming porous and weaker. This can cause a person to experience more bone fractures due to injuries.
Currently, there is no cure for osteoporosis. However, treatment options, such as infusion therapy, are available. This therapy involves injecting medication directly into the bloodstream to help strengthen bones and reduce the risk of fractures.
In this article, we will explore what infusion therapy is, how it works, and its potential side effects.
Infusion therapy is a method of administering medications, fluids, and other products to a person. A doctor will inject the medication into the body either through a needle or a catheter, which is a tube.
Intravenous therapy is one of the
Other forms of infusion or injectable therapies include:
- Epidural: This method involves injecting medication into the
epidural spaceof the spine.
- Intramuscular: This method involves injecting medication into a specific
muscleor group of muscles.
- Subcutaneous: This method involves injecting medication into the
subcutaneous tissue, the fatty layer of tissue beneath the skin.
The most common type of infusion therapy for osteoporosis is bisphosphonates. Examples of intravenous bisphosphonates include zoledronic acid (Reclast) and ibandronate (Boniva).
Infusion therapy allows for the direct injection of medication into the bloodstream and the cardiovascular system. In this way, the medication
These drugs are available in a variety of formulations. Zoledronic acid and ibandronate are examples of bisphosphonates that people can receive through infusion therapy.
These bisphosphonates work by
By inhibiting farnesyl pyrophosphate synthase, bisphosphonates are able to
Evidence suggests that a person should receive intravenous zoledronic acid once per year or once every 2 years. For females who are experiencing menopause, it is advisable to administer intravenous ibandronate every 3 months.
According to the Bone Health & Osteoporosis Foundation, side effects for all bisphosphonates can include bone, joint, or muscle pain.
Adverse effects of zoledronic acid
- low levels of calcium in the blood
- secondary hyperparathyroidism, a condition where the parathyroid glands create too much parathyroid hormone
- musculoskeletal pain
- atypical femur fractures
- osteonecrosis of the jaw
- atrial fibrillation
- ocular inflammation
A small number of individuals who receive intravenous bisphosphonate therapy may also experience:
- flu-like symptoms
Other treatment options available to help treat osteoporosis may include:
Denosumab is a bone
Hormone replacement therapy (HRT)
HRT is a type of medication that
HRT includes estrogen and progestogen, a synthetic version of progesterone. HRT may help prevent bone loss and reduce the risk of fractures.
Salmon calcitonin is a derivative of human calcitonin. It
Synthetic parathyroid hormone (PTH)
PTH is a synthetic version of the parathyroid hormone that the body produces. It
While constant exposure to PTH
Calcium and vitamin D
A doctor may also recommend that someone with osteoporosis take calcium and vitamin D supplements. A person needs sufficient vitamin D to form the hormone calcitriol. Calcitriol aids in the absorption of calcium, which in turn helps strengthen the bones and improve bone mass.
Infusion therapy involves injecting medication directly into the bloodstream to bypass barriers to absorption. Intravenous infusion therapy is a common form of administering medication in osteoporosis.
The first-line infusion therapy option for osteoporosis is typically a class of drugs known as bisphosphonates. Examples include ibandronate and zoledronic acid.
Side effects of bisphosphonates include bone joint or muscle pain, hypocalcemia, and rarely, flu-like symptoms and fever. Other treatment options for osteoporosis include denosumab, HRT, salmon calcitonin, and synthetic PTH.