Septic pelvic thrombophlebitis is a blood clot that blocks one or more pelvic veins. It can develop due to infection and inflammation in the pelvic region. The condition is uncommon and develops most often after childbirth.
Septic pelvic thrombophlebitis typically involves an infection and inflammatory response that leads to the development of a blood clot in one or more pelvic veins. It most commonly occurs after childbirth, especially a cesarean (C-section) delivery.
Once a pathogen, such as bacteria, enters the vein, it causes inflammation and may start the process of clot formation. An individual with septic pelvic thrombophlebitis can develop complications from both the infection and the blood clot.
In this article, we will cover the symptoms, causes, and treatments for septic pelvic thrombophlebitis.
Septic pelvic thrombophlebitis is a blood clot that develops due to an infection and subsequent inflammation. The blood clot blocks one or more of the pelvic veins.
Different types of infections, including bacteria and fungi, may lead to the infection. Staphylococcus aureus is the
Doctors divide septic pelvic thrombophlebitis into
In most cases, symptoms start 2–4 days after delivery. Experts consider the condition rare. A
The condition can become life threatening. The mortality rate in patients that develop septic pelvic thrombophlebitis is about 4.4%.
The cause of septic pelvic thrombophlebitis is an infection that causes an inflammatory response, which leads to the formation of a blood clot. Doctors theorize that complications with delivery or surgery may lead to an infection and pus formation in the wall of the vein, triggering the condition.
Doctors do not completely understand why it may occur in some people after childbirth. However, a combination of factors appears to make it more likely to occur after delivery.
For example, pregnancy changes the plasma levels of clotting factors, which may increase the risk of a blood clot developing. In addition, conditions before or after childbirth, such as an infection of the amniotic fluid, may increase the risk.
Researchers have identified certain factors that increase a person’s chances of developing septic pelvic thrombophlebitis, such as:
- C-section delivery: Septic pelvic thrombophlebitis occurs
most oftenafter a C-section delivery than during vaginal births.
- Age: Women under 20 years of age appear to have an increased risk of the condition.
- Race: Septic pelvic thrombophlebitis occurs more often in non-Hispanic Black individuals.
- Preeclampsia: This term refers to high blood pressure that develops during pregnancy.
- Chorioamnionitis: This is an infection of the amniotic fluid and the placenta.
- Twins: Having twins also increases the chances of developing the condition.
Symptoms typically start a few days after childbirth. They may vary slightly depending on the affected vein and
- fever, which may persist even with antibiotics
- lower abdominal pain on the side of the affected vein
- back pain
- abdominal tenderness
- increased respiratory rate
Symptoms can sometimes mimic other gynecological and obstetric conditions, such as endometritis, pelvic abscess, and wound infection after a C-section.
- Symptom history and physical exam: The doctor may check for lower abdominal tenderness and fever.
- Blood cultures: In some cases, blood cultures test positive for an infection, and the white blood cell count is high.
- Imaging tests: Doctors may order certain imaging tests to view pictures of the pelvic area and veins. For example, a CT scan may help detect the enlargement of an ovarian vein and possibly the presence of a blood clot in the vein. In some cases, a doctor may order an ultrasound to rule out other conditions and diagnoses.
Prompt treatment helps
Usually, treatment includes broad-spectrum antibiotics to treat the infection. However, a
Doctors may also administer an anticoagulant, or blood thinner, to break up the blood clot. The duration and type of medication may vary according to their clinical judgment. Commonly, they use heparin.
A treatment plan may also include supportive care, such as medication for pain and to make the person more comfortable. Careful monitoring is also vital to ensure the antibiotics are working and the clot formation does not worsen.
Septic pelvic thrombophlebitis is a rare condition that involves the development of a blood clot in the pelvic veins. This typically occurs due to an infection and subsequent inflammation. It is most commonly a postpartum complication, primarily after a C-section. Symptoms, such as fever and lower abdominal pain, usually start a few days after childbirth.
Treatment often includes antibiotics to eliminate the infection and blood thinner medications to break up the blood clot.