A simple surgical procedure on the kidneys touted as a revolutionary treatment for high blood pressure turns out to be not so revolutionary after all. In a first its kind, a Norwegian clinical trial shows that established, standard drug treatment works better than the new surgical procedure, reports ScienceNordic. See full story here.
Some patients with high blood pressure are resistant to commonly used hypertension medication. New hope was raised for these patients a few years ago with the introduction of a simple surgical procedure called renal sympathetic denervation (RDN).
As recently as 2012, the method was referred to as a possible revolution in hypertension treatment. Tens of thousands of patients have already undergone the procedure in some European countries.
But Chief Physician Aud Høieggen of Oslo University Hospital thinks the scientific basis for the RDN-method is weak. In a study published this week in the prestigious medical journal Hypertension, Aud Høieggen and her researcher colleagues show that the new surgical procedure in fact is less effective than established drug treatment methods.
Høieggen is eager to compare the results from the Oslo study with those of a forthcoming American study, due later this March.
Adjusted Drug Treatment Is Superior to Renal Sympathetic Denervation in Patients With True Treatment-Resistant Hypertension, Fadl Elmula M. Fadl Elmula, Pavel Hoffmann, Anne C. Larstorp, Eigil Fossum, Magne Brekke, Sverre E. Kjeldsen, Eyvind Gjønnæss, Ulla Hjørnholm, Vibeke N. Kjær, Morten Rostrup, Ingrid Os, Aud Stenehjem, Aud Høieggen, doi: 10.1161/HYPERTENSIONAHA.114.03246, published online 3 March 2014.