Myrbetriq interactions: Alcohol, medications, and other factors

Myrbetriq interactions with other medications  

Before you start treatment with Myrbetriq, tell your doctor and pharmacist which prescription, over-the-counter, and other medications you take. By sharing this information with them, you may help prevent possible interactions. (To learn whether Myrbetriq interacts with supplements, herbs, or vitamins, see the “Myrbetriq and other interactions” section.)

If you have questions about what drugs should not be taken with Myrbetriq or drug interactions that may affect you, ask your doctor or pharmacist.

Here’s a table of drugs that can interact with Myrbetriq. Keep in mind that this table doesn’t include all drugs that may interact with Myrbetriq. Some of these interactions are described in detail just below in “Drug interactions in depth.”

When to avoid Myrbetriq

In some cases, factors or conditions could prevent your doctor from prescribing Myrbetriq due to the risk of harm. These are known as contraindications. The contraindications of Myrbetriq include:

Having had an allergic reaction to Myrbetriq or any of its ingredients

If you have had an allergic reaction to Myrbetriq or any of its ingredients in the past, your doctor will likely not prescribe Myrbetriq. Taking the drug could cause another allergic reaction. You can ask them about other treatments that may be better choices for you.

Note: Before you start treatment with Myrbetriq, it’s important to tell your doctor if this contraindication applies to you. They can determine whether to prescribe Myrbetriq.

Myrbetriq interaction with alcohol

There aren’t any known interactions between Myrbetriq and alcohol. However, your doctor may advise you to avoid or limit alcohol consumption during Myrbetriq treatment.

This is because drinking alcohol while taking the drug may worsen some of Myrbetriq’s side effects or make them more likely to occur. For example, you may experience:

• headache
• dizziness
• urinary tract infections

Alcohol can also worsen the condition you’re receiving Myrbetriq to treat. For example, if you have an overactive bladder, drinking alcohol may worsen your symptoms because it can increase urination.

If you have questions about drinking alcohol while taking Myrbetriq, talk with your doctor.

Drug interactions in depth

Here’s a closer look at certain drug interactions of Myrbetriq.

Certain beta-blockers

Myrbetriq can interact with certain beta-blockers, which treat high blood pressure and certain heart conditions.

Interaction result: Taking Myrbetriq with certain beta-blockers can increase the risk of side effects from the beta-blocker. Examples of these side effects can include low blood pressure and a slow heartbeat.

Interaction explained: Myrbetriq reduces the action of an enzyme (a type of protein) that helps clear certain beta-blockers from your body. This enzyme is called cytochrome p450 2D6 (CYP2D6). By reducing the action of CYP2D6, Myrbetriq can increase the level of these beta-blockers in your body. Higher levels of beta-blockers are more likely to cause side effects.

Examples of beta-blocker drugs: Here are some beta-blockers that may interact with Myrbetriq:

• metoprolol (Lopressor, others)
• nebivolol (Bystolic)
• propranolol (Inderal LA, InnoPran XL)
• timolol (Timoptic, others)

Steps you or your doctor may take: If your doctor prescribes Myrbetriq with one of the beta-blockers listed above, they will likely monitor you more closely for side effects of the beta-blocker. For example, they may monitor your blood pressure and heart rate. If needed, your doctor may lower your dosage of the beta-blocker.

If you take Myrbetriq with a beta-blocker, tell your doctor if you have any new or increased side effects, especially dizziness or fainting.

If you have questions about taking Myrbetriq with a beta-blocker, talk with your doctor or pharmacist.

Anticholinergics

Myrbetriq can interact with anticholinergic drugs, which treat overactive bladder.

Interaction result: Taking Myrbetriq with an anticholinergic for overactive bladder can raise your risk of urinary retention (being unable to empty your bladder).

Interaction explained: Myrbetriq and anticholinergics work in different ways to relax the muscle in the wall of your bladder. Taking them together can make this muscle relax too much, making it difficult to empty your bladder.

Examples of anticholinergic drugs: Here are some anticholinergics that may interact with Myrbetriq:

• darifenacin
• fesoterodine (Toviaz)
• oxybutynin (Oxytrol)
• solifenacin (Vesicare)
• tolterodine (Detrol, Detrol LA)
• trospium

Steps you or your doctor may take: If your doctor prescribes Myrbetriq with an anticholinergic to treat overactive bladder, they may prescribe a dosage of one or both medications that’s lower than usual.

If you take these drugs together, tell your doctor right away if you have symptoms of urinary retention. These can include:

• a weak stream of urine
• having trouble urinating or an inability to urinate
• needing to urinate again shortly after using the bathroom
• an intense need to urinate
• abdominal pain or swelling

If you have questions about taking Myrbetriq with an anticholinergic, talk with your doctor or pharmacist.

Tricyclic antidepressants

Myrbetriq can interact with tricyclic antidepressants, which treat depression and certain other conditions.

Interaction result: Taking Myrbetriq with a tricyclic antidepressant can raise your risk of side effects from the tricyclic antidepressant. Examples can include:

• sleepiness
• dizziness
• constipation
• trouble urinating

Interaction explained: Myrbetriq reduces the action of an enzyme (a type of protein) called cytochrome p450 2D6 (CYP2D6) that helps clear tricyclic antidepressants from your body. By reducing the action of CYP2D6, Myrbetriq can increase the level of tricyclic antidepressants in your body. Higher levels of these antidepressants are more likely to cause side effects.

Examples of tricyclic antidepressant drugs: Here are some tricyclic antidepressants that may interact with Myrbetriq:

• amitriptyline
• desipramine (Norpramin)
• nortriptyline (Pamelor)

Steps you or your doctor may take: If your doctor prescribes Myrbetriq with a tricyclic antidepressant, they will likely monitor you more closely for side effects of the antidepressant. For example, they may monitor your blood pressure. If needed, your doctor may lower your dosage of the antidepressant.

If you take Myrbetriq with a tricyclic antidepressant, tell your doctor if you have any new or increased side effects, especially sleepiness, dizziness, or trouble urinating.

If you have questions about taking Myrbetriq with a tricyclic antidepressant, talk with your doctor or pharmacist.

Myrbetriq and other interactions

Myrbetriq may have other interactions, such as with supplements, foods, vaccines, or even lab tests. You’ll find details below. Keep in mind that the following information does not include all other possible interactions with Myrbetriq.

Myrbetriq interactions with supplements

It’s possible for drugs to interact with supplements such as vitamins and herbs.

Myrbetriq and herbs

There are no specific reports of herbs interacting with Myrbetriq. However, that doesn’t mean herbal interactions won’t occur or be recognized in the future. Because of this, it’s important to check with your doctor or pharmacist before taking any of these products during Myrbetriq treatment.

Myrbetriq and vitamins

There are no specific reports of vitamins interacting with Myrbetriq. However, that doesn’t mean vitamin interactions won’t occur or be recognized in the future. Because of this, you should talk with your doctor or pharmacist before taking any vitamin product with Myrbetriq.

Myrbetriq interactions with food

There were no reports of food interactions with Myrbetriq. If you’d like to learn more about eating certain foods during treatment with Myrbetriq, talk with your doctor.

Myrbetriq and vaccines

There aren’t any known interactions between Myrbetriq and vaccines. Talk with your doctor or pharmacist to see whether you’re due for any vaccines.

Myrbetriq interactions with lab tests

Myrbetriq isn’t known to interact with any lab tests. If you have concerns about this medication interacting with lab tests, talk with your doctor.

MYRBETRIQ INTERACTION WITH CANNABIS OR CBD

Cannabis (often called marijuana) and cannabis products, such as cannabidiol (CBD), have not been specifically reported to interact with Myrbetriq. However, as with any drug or supplement, talk with your doctor before using cannabis in combination with Myrbetriq. The impact of cannabis may affect how well you stick to your Myrbetriq treatment plan.

Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.

Myrbetriq and health-related interactions

Certain medical conditions and other factors may increase the risk of interactions with Myrbetriq. Before you take this drug, be sure to talk with your doctor about your health history. Myrbetriq may not be the right treatment option if you have certain medical conditions or other factors affecting your health.

Health conditions or factors that might interact with Myrbetriq include:

• High blood pressure: If you have high blood pressure, taking Myrbetriq could make it worse. Talk with your doctor about whether Myrbetriq is right for you. If you take Myrbetriq, your doctor will likely check your blood pressure more often than usual.
• Bladder outlet obstruction: If you have an obstruction (blockage) that makes it hard for urine to flow out of your bladder, taking Myrbetriq could cause urinary retention (being unable to empty your bladder). Conditions that can cause a bladder outlet obstruction include bladder stones and an enlarged prostate gland. If you have one of these conditions, talk with your doctor about whether Myrbetriq is right for you.
• Kidney or liver problems: If you have a kidney or liver problem, you may have a raised risk of side effects with Myrbetriq. This is because your kidneys and liver help clear Mybetriq from your body. If these organs don’t work well, Myrbetriq could build up in your body. Talk with your doctor about whether Myrbetriq is right for you. If you take Myrbetriq, your doctor may prescribe a Myrbetriq dosage that’s lower than usual.
• Allergic reaction: If you’ve had an allergic reaction to Myrbetriq or any of its ingredients, your doctor will likely not prescribe Myrbetriq. Taking the drug could cause another allergic reaction. You can ask them about other treatments that may be better choices for you.
• Breastfeeding: It’s not known whether it’s safe to use Myrbetriq while breastfeeding. There isn’t enough information to determine whether the drug passes into breast milk or what effects Myrbetriq may have on a child who is breastfed. If you’re breastfeeding or planning to, talk with your doctor before using Myrbetriq. They can talk with you about treatment options and ways to feed your child.
• Pregnancy: There haven’t been enough clinical trials to determine whether Myrbetriq is safe to use while pregnant. Animal studies show that the drug may cause congenital anomalies (commonly known as birth defects) or pregnancy loss. However, it’s important to note that animal studies don’t always indicate what may happen in humans. If you’re pregnant or planning to become pregnant, tell your doctor before starting Myrbetriq. They can advise you on the right treatment plan for you.

FAQs about Myrbetriq and interactions

Here are some frequently asked questions about Myrbetriq and possible interactions.

Can you take Myrbetriq with antibiotics?

Yes, it’s usually safe to take Myrbetriq with antibiotics. There are no specific reports of Myrbetriq interacting with antibiotics.

However, Myrbetriq and antibiotics can cause some similar side effects, such as nausea and diarrhea. This means you may be more likely to have these side effects if you take Myrbetriq with an antibiotic.

If you have questions about taking Myrbetriq with an antibiotic, talk with your doctor or pharmacist.

Can Myrbetriq and metformin be taken together?

Yes, Myrbetriq can usually be taken with metformin. Studies show that these drugs do not interact in a serious way.

However, because Myrbetriq and metformin share some similar side effects, such as nausea and diarrhea, you may be more likely to have these side effects if you take Myrbetriq with metformin.

If you have questions about taking Myrbetriq with metformin, talk with your doctor or pharmacist.

Preventing interactions

You can take certain steps to help prevent interactions with Myrbetriq. Your doctor and pharmacist are key resources, so reach out to them before starting treatment. For example, you should plan to do the following:

• Let them know if you drink alcohol or use cannabis.
• Tell them about any other medications you take, as well as any supplements, herbs, and vitamins.
• Create a medication list, which your doctor and pharmacist can help you fill out.

It’s also important to read the Myrbetriq label and other paperwork that may come with the drug. The label may have colored stickers that mention an interaction. And the paperwork, sometimes called the medication guide or patient package insert, may contain details about interactions.

If Myrbetriq doesn’t come with paperwork, you can ask your pharmacist to print a copy. If you need help reading or understanding this information, ask your doctor or pharmacist.

You can also help prevent interactions with Myrbetriq by taking it exactly as your doctor prescribes.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.