Granulomas are masses of immune cells that develop due to inflammation. They can occur in people with Crohn’s disease. However, not everyone with Crohn’s develops granulomas.
Crohn’s disease (CD) is a chronic inflammatory bowel disease that affects the digestive tract. It affects
Experts do not know the exact cause of Crohn’s disease. However, the immune system, genetics, and lifestyle factors may play a role.
Granulomas are collections of immune cells that form when there is inflammation in the body. They may occur in people with Crohn’s disease.
This article discusses granulomas in people with Crohn’s disease, exploring their causes, symptoms, and treatment.
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Granulomas are a common symptom of Crohn’s disease and may help doctors differentiate between Crohn’s and other inflammatory bowel disorders, such as ulcerative colitis.
However, not everyone with Crohn’s disease develops them.
However, experts do not know exactly why granulomas occur in some people with Crohn’s disease. One
One
There is no evidence to suggest that Crohn’s disease symptoms are different in people with granulomas.
The most common symptoms of the condition
- diarrhea
- cramping and pain in the abdomen
- weight loss
Other symptoms may include:
Current research about granulomas in people with Crohn’s disease is lacking.
A
Another
Doctors
The treatment is the same regardless of whether a person has granulomas.
Treatment aims to manage inflammation and prevent flare-ups.
Medications for Crohn’s disease include:
- aminosalicylates
- corticosteroids
- immunomodulators
Doctors may also recommend biologic therapies, such as alpha therapies and anti-tumor necrosis factors, to neutralize inflammation-causing proteins.
Additionally, doctors may prescribe antibiotics for Crohn’s disease complications, such as infection, and medications to treat symptoms, such as diarrhea.
Because
Surgery for this condition may involve:
- small bowel resection
- large bowel resection or a subtotal colectomy
- proctocolectomy
- ileostomy
Granulomas occur in response to inflammation in the body and consist of a collection of immune cells.
While they may occur in people with Crohn’s disease, not everyone with the condition develops them.
Some research suggests that people with granulomas have a more aggressive type of Crohn’s disease. They may be more likely to need surgery than those without granulomas.