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Lipozene is a popular diet pill for weight loss. It contains a soluble fiber called glucomannan that absorbs water to create a thick gel. This fiber may be linked to weight loss.

Lipozene may have potential benefits for some people. However, the weight loss effects are usually mild, and it is not right for everyone.

Diet pills, such as Lipozene, are not replacements for proven weight control methods, such as eating a healthy diet and exercising regularly.

This article explores the safety of Lipozene, as well as its benefits, side effects, and effectiveness.

Lipozene is a branded dietary weight loss supplement. It contains glucomannan as an active ingredient. Glucomannan is a fiber from the root of the konjac plant, Amorphophallus konjac.

Glucomannan is a soluble fiber that absorbs many times its weight in water. Because of this, konjac products are popular thickeners in some foods.

The konjac root and its compounds are popular weight loss aids because of this fiber and its ability to absorb water.

Learn more about the benefits of konjac here.

Lipozene may be a suitable option for those who wish to lose weight by reducing their calorie intake. As Lipozene can make a person feel full more quickly, they may eat less, thereby reducing their calories and potentially losing weight over time.

That said, results from research are mixed regarding how effective Lipozene is for weight loss. Older research found that glucomannan resulted in significant weight loss in people with overweight and obesity, but there is little data on how long the weight loss effects lasted.

In a 2020 study, another glucomannan weight loss brand, PGX, was found to have weight loss benefits in people with overweight and obesity. However, results are mixed and there is little data on how long the weight loss effects may last.

Lipozene may also suit people who want to try a low calorie weight loss pill that uses natural active ingredients. However, Lipozene contains gelatin, which means it is not suitable for vegetarians or vegans.

Other people who Lipozene may not be suitable for include those with diabetes. This is because Lipozene can block the absorption of some diabetes medications.

Additionally, those who have difficulty swallowing tablets or capsules may wish to avoid Lipozene.

A person should always talk to a doctor before trying Lipozene to ensure it is safe for them to take.

The active ingredient in Lipozene, glucomannan, has been found to be well tolerated in two older studies from 2005 and 2013. Overall, it is safe when people use it as the manufacturers direct.

However, it is important for a person to stay well hydrated when taking glucomannan products because it can absorb up to 200 times its weight in water.

Additionally, glucomannan capsules may be safer than powders. As a very absorbent substance, glucomannan can expand before it reaches the stomach, increasing a person’s risk of choking or a blockage in their digestive system.

A person should not exceed the company’s recommended dose and follow instructions on how and when to take Lipozene.

The benefits of glucomannan relate to its specific type of soluble, fermentable dietary fiber.

A review in the International Journal of Biological Macromolecules notes that glucomannan fiber may help:

Many of these benefits come from how glucomannan behaves in the body. Glucomannan absorbs many times its weight in water, forming a gel-like substance that the digestive system processes with food.

The sections below detail some specific potential benefits.

It may keep the body full

Taking Lipozene with a full glass of water before each meal creates a thick, gel-like substance in the stomach. This substance leaves less room in the stomach for food.

Because of this, a person who takes Lipozene may feel full sooner, which may reduce the chance of overeating.

It may reduce calories from meals

As glucomannan can make the body feel fuller, it might reduce the number of calories a person eats with each meal. If the person consumes fewer calories than they burn each day, this could lead to weight loss over time.

The fiber itself is also low in calories, so taking it does not add much to the diet.

It may reduce caloric intake from other sources

Glucomannan may also help a person lose weight by reducing the energy they absorb. Soluble fibers, such as glucomannan, may reduce the absorption of nutrients, such as fats.

This means that the body might take up less energy from these food sources and, instead, pass these calories out with waste.

It is a source of prebiotic fiber

Glucomannan fiber is also prebiotic. This means that it feeds the healthy bacteria that colonize the intestines.

The International Journal of Biological Macromolecules review notes that the stomach does not digest the fiber. Instead, the fiber passes through to the intestines, where the intestinal bacteria can ferment it and use it as fuel.

This process is important, as the health of the intestinal microorganisms influences the overall well-being of the body.

A study in Current Developments in Nutrition notes the benefits of prebiotic compounds, including their ability to:

  • increase healthy bacteria in the intestines
  • increase mineral absorption
  • decrease harmful bacteria in the gut
  • decrease allergy risk
  • cut the harmful fermentation of proteins in the gut
  • improve the immune system response

Although not every prebiotic fiber will act the same way, eating a diet rich in prebiotics may help ensure that the intestinal flora is healthy.

It has simple active ingredients

Another potential benefit is that Lipozene is a relatively simple form of weight loss supplement.

Although some pills may contain stimulants, laxatives, or other additives, the only active ingredient in Lipozene is glucomannan.

So, the product may be an option for people looking for more straightforward ingredients to help them with weight loss.

Most people tolerate glucomannan well. However, some people may be more sensitive to soluble fibers, and mild reactions in the digestive system may occur.

Mild side effects from taking glucomannan may include:

Some side effects may be worse if the person does not drink enough water along with the glucomannan, as the fiber is highly absorbent and may take water from the body.

Glucomannan may also reduce the absorption of certain medications. A person can talk with a doctor before taking Lipozene to ensure that it will not interact with any of their medications.

The following sections look at some specific risks in more detail.


There is a risk of choking if an individual does not drink enough water along with Lipozene capsules. Specifically, if the capsules become stuck in the throat, they may expand and swell, blocking the esophagus.

For this reason, people who have difficulty swallowing capsules may want to avoid Lipozene.

Anyone who is experiencing serious side effects — such as chest pain, difficulty breathing, or difficulty swallowing — after taking Lipozene must seek immediate medical attention.

Reactions from other ingredients

Although glucomannan and konjac root are not common allergens, some people may be more sensitive to the added ingredients in Lipozene.

Aside from glucomannan from the konjac root, Lipozene capsules also contain:

  • gelatin
  • microcrystalline cellulose
  • magnesium silicate
  • stearic acid
  • titanium dioxide
  • FD&C Blue #1

The pros of Lipozene dietary supplements include that it:

  • may enable weight loss
  • may prevent a person from overeating
  • may reduce the absorption of fat
  • may work as a prebiotic, increasing healthy bacteria in the intestines
  • is additive-free
  • is laxative-free
  • is stimulant-free
  • may reduce levels of glucose
  • may reduce cholesterol
  • may reduce fats in the blood
  • may lower blood pressure

The cons of Lipozene dietary supplements include that it:

  • only yields mild, inconsistent weight loss in research studies
  • is not suitable for vegetarians or vegans
  • may reduce the effectiveness of certain medications
  • may cause stomach discomfort, nausea, diarrhea, and constipation
  • risk of choking

Typically, the effectiveness of Lipozene for weight loss is mild. A review in Current Obesity Reports notes a broad body of research, including nine clinical trials, suggesting that glucomannan may be mildly effective for weight loss.

The researchers note weight loss of 0.5–1.7 pounds after taking glucomannan for 5.2 weeks.

However, an older 2013 study suggests that glucomannan does not promote weight loss, alter body composition, or change feelings of hunger or fullness.

For some people, these mixed results may be enough to justify taking Lipozene to boost their diet and weight loss goals. Other people may feel they do not justify the cost or potential side effects.

Learn more about the effectiveness of weight loss pills here.

The Lipozene website recommends taking two capsules and a full glass of water 30 minutes before each meal, up to six capsules each day.

Dosage recommendation

A two-capsule serving of Lipozene contains 1,500 milligrams of konjac fiber. This serving should always include at least 8 ounces of water.

At the time of publishing, Lipozene costs $29.95. Each bottle contains 60 capsules, equal to 30 two-capsule servings.

The company also offers promotions, such as buy one get one free.

The manufacturer charges a processing fee of $1.35 when shipping the item. Additionally, the manufacturer will charge a fee of $1.35 if a person returns the supplement.

There is a 30-day money-back guarantee. If a person is not happy with the effects of the supplement within 30 days of receiving their order, the manufacturer will refund the money minus a processing fee of $1.35.

Taking glucomannan or Lizopene for weight loss appears to produce mild results in some cases. However, no dietary supplement is a replacement for other healthy weight loss habits.

Anyone who is looking to lose weight will still need to make changes to their diet and lifestyle. These changes often include eating a healthy diet, reducing caloric intake, and getting regular exercise.

Anyone who is worried about their weight should work with a doctor to create an individualized plan for weight loss.

Learn how to lose weight fast naturally here.

People who are looking to lose weight may wish to change their diet and engage in more physical activity. The sections below cover these lifestyle changes in more detail.

Healthy diet

People should ensure that they are eating a healthy, balanced diet if they wish to manage their weight.

Each individual will need a slightly different number of calories per day to maintain, gain, or lose weight. The United States Department of Agriculture (USDA) has a free tool on its website that people can use to find out their calorie needs.

The Dietary Guidelines for Americans 2020–2025 recommend people eat the following for a healthy, balanced diet:

  • all types of vegetables, including leafy greens and starchy vegetables
  • whole fruits
  • grains, half of which should be whole grain
  • dairy, including fat-free, low fat, lactose-free, and soy milk, yogurt, and cheese
  • protein, such as lean meat, poultry, legumes, and soy products
  • oils, such as vegetable oils

People should limit the amount of food they eat with high sodium, added sugars, and saturated fats.

Meal kit deliveries

Although people can meal plan and cook food in batches to eat throughout the week, others may prefer to use meal kit delivery services that offer food that may help people lose weight.

Some meal kit delivery services that may offer calorie-conscious meals include:

  • Blue Apron: This company offers low-calorie, carbohydrate-conscious, and diabetes-friendly meals. Blue Apron also sells meals that contain 600 calories or fewer. Learn more about Blue Apron here.
  • Trifecta: This company offers meals that contain 350–500 calories, which may help support weight loss. Trifecta uses organic ingredients and has meals suitable for people with ketogenic, paleo, and plant-based diets. Learn more about Trifecta here.
  • Factor: This company states that most of its meals contain around 600 calories. Factor has meals that are suitable for people with various diets, such as low calorie, high protein, and plant-based. Learn more about Factor here.

Learn more about meal kits for weight loss here.

Physical activity

People should also engage in regular physical activity to lose or maintain weight.

The Centers for Disease Control and Prevention (CDC) state that people should not rely only on physical activity to lose weight. A combination of eating healthy food and exercising regularly is more likely to help a person reach their health goals.

People should aim for 150 minutes of moderate-intensity cardio, 75 minutes of vigorous-intensity cardio, or a combination of the two per week. Getting this amount of activity can help people maintain weight loss and lose weight while eating a healthy diet.

Anyone considering Lipozene should speak with a doctor or qualified nutrition professional before making a purchase. A person can talk to a doctor about their weight loss goals and medical history to make sure that Lipozene will be safe for them to use.

Although Lipozene states it is not aware of any medications or supplements that Lipozene can interact with, a person should consider any medication they take and discuss this with a doctor before trying Lipozene.

Additionally, some people may experience side effects while taking Lipozine, including stomach discomfort, nausea, diarrhea, and constipation. Those who experience these side effects should stop taking Lipozene and consult a doctor.

Additionally, anyone who is experiencing chest pain, difficulty breathing, or difficulty swallowing after taking Lipozene should seek immediate medical attention.

To get advice on how to lose weight safely, a person can speak to a licensed dietician or their primary healthcare provider.

Below are answers to the top frequently asked questions about Lipozene.

What is Lipozene used for?

Lipozene is a dietary weight loss supplement. It may help reduce a person’s appetite and make them feel full more quickly when they eat.

Does Lipozene lower cholesterol?

Research suggests that glucomannan, the active ingredient in Lipozene, may help reduce cholesterol.

Is Lipozene dangerous?

Research shows that the active ingredient in Lipozene, glucomannan, is tolerated well. However, it may cause mild side effects such as stomach pain, gas, constipation, and diarrhea.

There is a risk of dehydration and choking when taking Lipozene. This is because glucomannan is extremely effective at absorbing water, and, if not swallowed properly, can expand in the throat and become a choking hazard.

Glucomannan may also reduce the absorption of some medications.

A person should always speak with a doctor before trying Lipozene for weight loss.

Lipozene is a well-reviewed dietary supplement. The active ingredient, called glucomannan, is a natural fiber that may benefit the body when a person takes it regularly with plenty of water.

No supplement can replace dietary and lifestyle changes for weight loss. Taking Lipozene may help support weight loss efforts for some people, though any additional weight loss resulting from the supplement is typically mild.