Alcohol may increase the risk of breast cancer because it causes a change in raises estrogen, reduces folate absorption, and causes damage to cell DNA. Alcohol may also increase cancer risk through oxidative stress and impairing how the body eliminates harmful chemicals.
The ethanol in alcoholic drinks may cause an increased risk of breast cancer.
In this article, we look at the reasons alcohol may increase the risk of breast cancer, how types and amounts of alcohol relate to risk, and whether there is a safe limit to drink.
According to the
Data from 118 different studies suggests that light drinkers have a slight increase in breast cancer risk compared with those who do not drink alcohol. Moderate drinkers and heavy drinkers have a higher risk.
In comparison with females who do not drink any alcohol,
- three alcoholic drinks a week leads to a 15% increased risk
- an increased risk of 10% for every additional drink people have each day on a regular basis
In females between the ages of 9–15 years, drinking between three and five alcoholic drinks each week triples the risk of developing noncancerous breast lumps. Some types of noncancerous breast lumps may link to an increased risk of breast cancer in later life.
Although there is little research on alcohol and recurrence,
Low folate levels may have a link to an increased risk of breast cancer.
Alcohol may reduce how well the body absorbs certain nutrients, including folate. Folate is an important vitamin for keeping cells healthy. Heavy drinkers may have particularly low absorption of nutrients and low folate levels.
Estrogen is a hormone that plays an important role in breast tissue growth and development. Higher estrogen levels may increase the risk of breast cancer. Alcohol can raise estrogen levels.
Alcohol may also increase other hormones that have a link to hormone receptor-positive breast cancer.
Alcohol may cause damage to DNA in cells, which can increase the risk of breast cancer. Alcohol can convert to a chemical called acetaldehyde, which can damage cell DNA.
Alcohol can also cause oxidative stress, which can cause cell damage and increase cancer risk.
Alcohol can slow down how well the body is able to get rid of harmful chemicals, such as substances in tobacco smoke. It also increases how easily these chemicals enter cells in the lining of the upper section of the digestive tract.
In addition, consuming alcohol can increase calorie intake, which may be a factor in developing obesity. This can increase breast cancer risk.
Alcoholic drinks, including beer, wine, and liquor, contain ethanol. According to the
Ethanol amounts can vary in different alcoholic drinks, but the following standard-size drinks usually contain around half an ounce (oz) of ethanol:
- 12 oz beer
- 5 oz wine
- 1.5 oz of 80-proof liquor
Larger quantities, or stronger drinks, will contain higher levels of ethanol.
It is likely how much alcohol people consume over time, rather than the type of alcoholic drink, which increases the risk of cancer.
According to the
However, if people choose to drink alcohol, the guideline suggests no more than one drink a day for females and no more than two drinks a day for males.
In addition, females typically have less water in their bodies. As the body stores alcohol mostly in body water, the blood-alcohol concentration would be higher for females despite them drinking the same amount of alcohol.
Research has shown a consistent link between alcohol consumption and increased risk of breast cancer. This may be
Alcohol may also impair the body’s ability to eliminate harmful chemicals, and excess calorie intake from alcohol may lead to weight gain, which may also be a risk factor.
Light drinkers have a slight increase in risk, while moderate and heavy drinkers have a
Avoiding or limiting alcohol intake may be an important factor in helping to reduce the risk of breast cancer.