Black women are more than twice as likely as white women to receive a diagnosis of triple-negative breast cancer (TNBC).
Mortality rates for TNBC are also
Researchers believe that a number of factors, including both biological and social factors, contribute to the higher rates of TNBC among Black women and their less positive outlook.
In this article, we look at the science behind this disparity and discuss the outlook for Black women with TNBC in more detail.
However, research suggests that the prevalence of TNBC among Black women varies based on where they were born.
Compared with women born in the U.S., the prevalence of breast cancer was 13% and 47% lower among women born in the Caribbean and East Africa, respectively.
The researchers say that there are many possible causes of this variation in prevalence among Black women.
Possible factors include:
- health behaviors
- social structures
Researchers believe that a combination of factors contributes to the increased risk of TNBC among Black women.
Tor example, 46% of the Black women in the study had a TP53 mutation, compared with 27% of the white women.
TP53 is the most commonly mutated gene in breast cancer. When functioning normally, the TP53 gene acts as a tumor suppressor and stops cells from growing out of control. When it mutates, the TP53 gene can cause cells to replicate rapidly.
Obesity raises the risk of several cancers. In the U.S., obesity disproportionately affects Black women.
However, it is important to note that non-Hispanic white women accounted for the majority of the cohort.
A number of social factors likely contribute to the development of obesity and can, in turn, lead to the development of TNBC. These
- income disparity
- lack of access to a variety of nutritious foods, such as fresh vegetables
- lack of exercise
- high intake of inexpensive foods that are high in calories
Numerous social factors may play a role in the high rates of TNBC in Black women. These
- unsafe neighborhoods
- lack of access to healthcare
- social stress
A growing body of research suggests that women with a lower socioeconomic status are more likely to receive a diagnosis of breast cancer in the later stages. Compared with white women, Black women are
Problems with social inequality and unsafe neighborhoods may lead to higher rates of obesity among Black women, which is a risk factor for a number of cancers, including TNBC.
Research suggests that Black women have higher mortality rates from breast cancer than white women.
Black women are more likely to receive a diagnosis at a later stage of disease than their white counterparts. They also have the lowest rates of survival for any stage of diagnosis.
Numerous studies have indicated that both treatment and outcomes for Black women differ significantly from the experience of white women across all forms of breast cancer.
Black women are less likely to receive the appropriate treatment that aligns with national guidelines. The same 2021 study found that Black women have a 31% lower chance of having surgery than white women and are 11% less likely to have chemotherapy.
Several factors may contribute to the disparity in care and treatment of Black women with breast cancer. These include:
- systemic racism
- communication issues with healthcare professionals
- less likely to receive the appropriate standard of care
- difficulties with travel to access care
- financial struggles
- difficulties taking time off work
All people deserve to receive a high standard of care to give them the best possible outlook. The standard of care for TNBC includes surgery, chemotherapy, and, in some cases, radiation therapy.
Although Black women may have an increased risk of TNBC, getting started on the right treatment can lead to the best possible outcomes. Anyone who is not satisfied with the response that they get from a healthcare professional should consider seeking a second opinion, if possible.