Mounjaro is a brand-name subcutaneous injection prescribed for type 2 diabetes. It contains the active drug tirzepatide. Mounjaro may not be safe to use during pregnancy and breastfeeding.
If you can become pregnant, it’s important to consider whether Mounjaro is a safe choice for you.
Your doctor will likely recommend not using Mounjaro while you’re pregnant. This is because it’s not known whether Mounjaro is safe to use during pregnancy. Pregnant people were not included in the drug’s clinical trials.
Based on animal studies, tirzepatide (the active ingredient in Mounjaro) may cause harm to a fetus.
If you’re pregnant or planning to become pregnant, talk with your doctor. They can recommend safe ways to help manage diabetes during this time.
Mounjaro and fertility
It’s not known whether Mounjaro affects fertility (the biological ability to conceive).
In animal studies, tirzepatide (the active ingredient in Mounjaro) didn’t affect male animals given the drug. Some female animals given tirzepatide had signs of reduced fertility. These signs were thought to be related to the females’ reduced food intake and body weight. However, animal studies do not always reflect how drugs affect humans.
If you have questions about Mounjaro and your fertility, talk with your doctor.
If you’re breastfeeding or planning to do so, it’s important to consider how Mounjaro may affect you and your child.
Your doctor will likely recommend not using Mounjaro while breastfeeding. It’s not known whether the drug is safe to use during this time. Researchers have not yet studied Mounjaro’s effects on breast milk.
If you’re breastfeeding or considering it, talk with your doctor before starting Mounjaro treatment. They can recommend safe ways to help manage diabetes while breastfeeding.
If you’re sexually active and you or your partner can become pregnant, it’s important to know how Mounjaro treatment may affect your birth control decisions.
It’s not known whether Mounjaro is safe to use during pregnancy. If you or your partner can become pregnant, talk with your doctor about your birth control needs during Mounjaro treatment.
For more information about using Mounjaro during pregnancy, see the “Mounjaro and pregnancy” section above.
It’s important to note that Mounjaro may interact with certain types of birth control pills. Mounjaro may reduce the effectiveness of hormonal birth control pills at certain times. This is during the first 4 weeks of Mounjaro treatment and for 4 weeks after each dose increase. (For more information about this medication’s typical dosing, refer to this article.)
If you take an oral form of hormonal birth control, your doctor will likely recommend either:
- switching to a non-oral birth control method, such as the patch or vaginal ring, or
- adding a barrier method of birth control, such as condoms
You may be able to switch back to your birth control pill 4 weeks after the last dose increase. If you have questions about this, talk with your doctor or pharmacist.
Besides learning about how Mounjaro may affect your reproductive health, you may want other information about Mounjaro. These additional articles might be helpful:
- More about Mounjaro. For information about other aspects of Mounjaro, refer to this article.
- Side effects. To learn about side effects of Mounjaro, see this article. You can also look at the Mounjaro prescribing information.
- Cost. If you’d like to learn about Mounjaro and cost, see this article.
- Interactions. For details about what Mounjaro interacts with, see this article.
- Details about type 2 diabetes. For details about type 2 diabetes, see our diabetes hub.
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Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.