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A Johns Hopkins study finds a decline in the blood sugar control of adults with diabetes in the Unites States. Fertnig/Getty Images
  • A new study finds that fewer people with diabetes in the U.S. are successfully maintaining healthy blood sugar levels.
  • Adequate blood pressure and low-density lipoprotein (LDL) cholesterol management — two other factors important for individuals with the condition — is also decreasing.
  • The study’s conclusions are a wake-up call for the tens of millions of adults with diabetes in the U.S., as the worrying trend increases their risk of major health complications.

According to the Centers for Disease Control and Prevention (CDC), 34.2 million of people in the U.S., which is 10.5% of the country’s population, have diabetes. Of them, 7.3 million, or 21.4%, have not yet received a diagnosis. The CDC also estimates that 34.5% of people over 18 years old, or 88 million, have prediabetes.

Researchers from the Johns Hopkins Bloomberg School of Public Health in Baltimore, MD, have just published the results of a nationwide study whose aim was to assess how well people with diabetes in the U.S. have been doing at maintaining blood glucose levels.

The study finds that over the last decade, people with diabetes in the U.S. have become significantly less successful at controlling their blood sugar.

The study’s senior author, Dr. Elizabeth Selvin, of the Bloomberg School’s Department of Epidemiology, said:

“These are concerning findings. There has been a real decline in glycemic control from a decade ago, and overall, only a small proportion of people with diabetes are simultaneously meeting the key goals of glycemic control, blood pressure control, and control of high cholesterol.”

The CDC notes that in the U.S., 90–95% of people with diabetes have type 2 diabetes. This condition occurs when the body is unable to use the insulin the pancreas produces, causing the sugar from food to accumulate in the bloodstream.

High blood sugar can cause cardiovascular disease and kidney disease, as well as problems with the nerves, eyes, and other organs. Diabetes can also lead to peripheral artery disease and others severe complications.

The study appears in The New England Journal of Medicine.

For people at risk of type 2 diabetes — including people with prediabetes — reaching or maintaining a moderate weight and becoming more physically active can help prevent the condition or delay its onset.

People with diabetes need to continually check their blood sugar, typically with a hemoglobin A1C finger prick test, to ensure it remains at an acceptable level.

A balanced diet and active lifestyle, as well as injectable insulin and other medications, can help an individual maintain glycemic control.

Managing diabetes is achievable, but it does require effort. Doing so means following the diabetes ABCs, that is, maintaining healthy levels of blood sugar, blood pressure, and LDL cholesterol.

The authors of the study analyzed data from the federal National Health and Nutrition Examination Survey. The survey tracks 5,000 individuals annually through interviews and clinical records.

The data examined for the study spanned the years 1999–2018 and encompassed 6,653 individuals who had received a diabetes diagnosis outside of pregnancy.

Between 1992 and 2002, 44% of the study sample had blood sugar under control, which was defined as having HbA1c levels below 7%. From 2007 to 2010, glycemic control was trending upward, to 57.4%. However, from 2015 to 2018, it dropped to 50.5%.

The researchers saw a similar trend for blood pressure control. Although management of hypertension was on the rise earlier on, it too decreased toward the end of the study period.

Between 1999 and 2002, 64% of the sample maintained blood pressure levels below 140/90 millimeters of mercury. In the period from 2011 to 2014, it was 74.2%, but between 2015 and 2018, it fell back to 70.4%.

Finally, people maintaining an LDL cholesterol below 130 milligrams per deciliter essentially stalled at 55.7% between 2015 and 2018. The number had doubled between 1999–2002 and 2007–2010, when it rose from 25.3% of the sample to 52.3%.

The number of people with diabetes maintaining control of all three ABC factors rose dramatically from 9% in 1999–2002 to 24.9% in 2007–2010, before dropping back to 22.2% between 2015 and 2018.

Dr. Michael Fang, a postdoctoral fellow at the Bloomberg School and lead author of the study, said:

“These trends are a wake-up call, since they mean that millions of Americans with diabetes are at higher risk [of] major complications. Our study suggests that worsening control of diabetes may already be having a detrimental effect at the national level.”

Citing earlier research, the study’s authors suggest what has changed may be physicians’ commitment to helping their patients achieve glycemic control due to its difficulty and potential hazards. These include life threatening hypoglycemia.

Dr. Selvin notes, however, that in recent years, new and improved diabetes drugs have become available. She suggests that if they carry less risk of hypoglycemia, the entire process of managing blood sugar levels may not be as complicated and daunting as physicians and patients might have come to expect.